BRD1, bromodomain containing 1

BRD1, bromodomain containing 1

• This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schizophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017]

• Gene Synonyms (bromodomain-containing protein 1, BR140-like protein, bromodomain and PHD finger-containing protein 2, BRL, BRPF1, BRPF2,)
• NCBI Gene ID: 23774
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R4W4
  UNIPROT ID#>>O95696
  UNIPROT ID#>>A0A024R4V5
  UNIPROT ID#>>Q59G93
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

bromodomain containing 1 interacts with:

• centrobin, centriole duplication and spindle assembly protein
  centrosomal protein 126
  centrosomal protein 70
  chromodomain helicase DNA binding protein 5
  DISC1 scaffold protein
  glutamine and serine rich 1
  H3 clustered histone 14
  homeobox containing 1
  inhibitor of growth family member 4
  inhibitor of growth family member 5
  Ly1 antibody reactive
  lysine methyltransferase 5B
  MIS18 binding protein 1
  mitochondrial ribosomal protein S14
  mitochondrial ribosomal protein S34
  MYST/Esa1 associated factor 6
  NOP2/Sun RNA methyltransferase 2
  oxidoreductase NAD-binding domain containing 1
  pleckstrin homology domain containing A4
  polybromo 1
  ribosomal protein L22 like 1
  ribosome binding protein 1
  signal recognition particle 72
  SS18L1 subunit of BAF chromatin remodeling complex
  tuftelin interacting protein 11
  vir like m6A methyltransferase associated
  zinc finger CCCH-type containing 15
  zinc finger protein 512B
  zinc finger RANBP2-type containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.