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TFIP11, tuftelin interacting protein 11

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TFIP11, tuftelin interacting protein 11

  • This gene encodes a protein component of the spliceosome that promotes the release of the lariat-intron during late-stage splicing through the recruitment of a pre-mRNA splicing factor called DEAH-box helicase 15. The encoded protein contains a G-patch domain, a hallmark of RNA-processing proteins, that binds DEAH-box helicase 15. This protein contains an atypical nuclear localization sequence as well as a nuclear speckle-targeting sequence, enabling it to localize to distinct speckled regions within the cell nucleus. Polymorphisms in this gene are associated with dental caries suggesting a role in amelogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

  • Gene Synonyms (tuftelin-interacting protein 11, septin and tuftelin-interacting protein 1, sip1/tuftelin interacting protein, NTR1, STIP, STIP-1, Spp382, TIP39, bK445C9.6,)
  • NCBI Gene ID: 24144
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>A0A024R1I7
    UNIPROT ID#>>Q9UBB9
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tuftelin interacting protein 11 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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