FUT8, fucosyltransferase 8

FUT8, fucosyltransferase 8

• This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]

• Gene Synonyms (CDGF, CDGF1, alpha-(1,6)-fucosyltransferase, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase, GDP-fucose--glycoprotein fucosyltransferase, alpha1-6FucT, fucosyltransferase 8 (alpha (1,6) fucosyltransferase), glycoprotein 6-alpha-L-fucosyltransferase,)
• NCBI Gene ID: 2530
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q546E0
  UNIPROT ID#>>A8K8P8
  UNIPROT ID#>>Q9BYC5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

fucosyltransferase 8 interacts with:

• 5-hydroxytryptamine receptor 3A
  5-hydroxytryptamine receptor 3C
  ADP ribosylation factor GTPase activating protein 2
  ADP ribosylation factor like GTPase 5A
  alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
  apoptotic chromatin condensation inducer 1
  beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
  bromodomain adjacent to zinc finger domain 1A
  CD200 receptor 1
  CEA cell adhesion molecule 21
  cholinergic receptor nicotinic alpha 9 subunit
  chondroitin sulfate N-acetylgalactosaminyltransferase 2
  coactivator associated arginine methyltransferase 1
  F-box protein 7
  fibrinogen like 2
  gamma-aminobutyric acid type A receptor subunit delta
  heterogeneous nuclear ribonucleoprotein D
  histone deacetylase 8
  integrin subunit alpha V
  intercellular adhesion molecule 3
  limb development membrane protein 1 like
  mannosidase alpha class 2A member 1
  mannosidase alpha class 2A member 2
  mannosyl-oligosaccharide glucosidase
  metal response element binding transcription factor 2
  metallophosphoesterase 1
  nuclear receptor corepressor 1
  olfactomedin 4
  phospholipid transfer protein
  plasmalemma vesicle associated protein
  protein tyrosine phosphatase receptor type U
  RAB guanine nucleotide exchange factor 1
  RAB1A, member RAS oncogene family
  RAB1B, member RAS oncogene family
  RAB5C, member RAS oncogene family
  ribosomal protein L27
  ring finger protein 4
  RPTOR independent companion of MTOR complex 2
  SEC23 homolog B, COPII coat complex component
  SEC24 homolog A, COPII coat complex component
  SEC24 homolog B, COPII coat complex component
  SEC24 homolog C, COPII coat complex component
  secretion associated Ras related GTPase 1A
  solute carrier family 25 member 17
  solute carrier family 30 member 5
  solute carrier family 39 member 4
  solute carrier family 9 member A6
  syntaxin 18
  trafficking protein particle complex 11
  trafficking protein particle complex 12
  trafficking protein particle complex 13
  trafficking protein particle complex 5
  transient receptor potential cation channel subfamily C member 6
  transmembrane protein 30B
  VPS53 subunit of GARP complex
  zinc finger and BTB domain containing 10

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.