STK39, serine/threonine kinase 39

STK39, serine/threonine kinase 39

• This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]

• Gene Synonyms (STE20/SPS1-related proline-alanine-rich protein kinase, STE20/SPS1 homolog, Ste20-like protein kinase, proline-alanine-rich STE20-related kinase, serine threonine kinase 39 (STE20/SPS1 homolog, yeast), serine/threonine-protein kinase 39, small intestine SPAK-like kinase, ste-20-related kinase, DCHT, PASK, SPAK,)
• NCBI Gene ID: 27347
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UEW8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serine/threonine kinase 39 interacts with:

• aristaless related homeobox
  atlastin GTPase 2
  killer cell lectin like receptor G2
  pleckstrin homology domain containing A4
  RELT like 1
  RELT like 2
  RELT TNF receptor
  serine/threonine kinase 39
  translocase of outer mitochondrial membrane 22
  TSC22 domain family member 4
  WNK lysine deficient protein kinase 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.