HOXB7, homeobox B7

HOXB7, homeobox B7

• This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008]

• Gene Synonyms (homeobox protein Hox-B7, homeo box 2C, homeo box B7, homeo box c1 protein, homeobox protein HHO.C1, homeobox protein Hox-2C, HHO.C1, HOX2, HOX2C, Hox-2.3,)
• NCBI Gene ID: 3217
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P09629
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

homeobox B7 interacts with:

• geminin DNA replication inhibitor
  inosine monophosphate dehydrogenase 1
  interleukin 1 receptor associated kinase 3
  NFKB inhibitor alpha
  PBX homeobox 1
  PBX/knotted 1 homeobox 1
  protein kinase, DNA-activated, catalytic subunit
  ubiquitin protein ligase E3 component n-recognin 3
  X-ray repair cross complementing 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.