MIP, major intrinsic protein of lens fiber

MIP, major intrinsic protein of lens fiber

• Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13. [provided by RefSeq, Jul 2008]

• Gene Synonyms (AQP0, CTRCT15, LIM1, MIP26, MP26, lens fiber major intrinsic protein, aquaporin 0,)
• NCBI Gene ID: 4284
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P30301
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

major intrinsic protein of lens fiber interacts with:

• CDGSH iron sulfur domain 2
  claudin 5
  endogenous retrovirus group FRD member 1, envelope
  ERGIC and golgi 3
  family with sequence similarity 209 member A
  glutathione peroxidase 8 (putative)
  golgi membrane protein 1
  leucine rich repeat containing 4C
  LHFPL tetraspan subfamily member 5
  major intrinsic protein of lens fiber
  mitochondrial fission factor
  mitochondrial ribosomal protein S18B
  mitochondrial rRNA methyltransferase 3
  mucin 1, cell surface associated
  PDZK1 interacting protein 1
  protein kinase cAMP-activated catalytic subunit alpha
  RELT like 2
  secretion associated Ras related GTPase 1A
  serine rich single-pass membrane protein 1
  solute carrier family 14 member 1 (Kidd blood group)
  solute carrier family 18 member A1
  sphingosine-1-phosphate lyase 1
  synapse associated protein 1
  synaptotagmin 1
  synaptotagmin 2
  syntaxin 1A
  thioredoxin related transmembrane protein 2
  transmembrane protein 139
  transmembrane protein 154
  transmembrane protein 52B
  zinc finger protein like 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.