SYT1, synaptotagmin 1

SYT1, synaptotagmin 1

• The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010]

• Gene Synonyms (synaptotagmin-1, synaptotagmin I, sytI, BAGOS, P65, SVP65, SYT,)
• NCBI Gene ID: 6857
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P21579
  UNIPROT ID#>>J3KQA0
  UNIPROT ID#>>A0A024RBE9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

synaptotagmin 1 interacts with:

• armadillo repeat containing 1
  autophagy related 16 like 1
  butyrophilin subfamily 2 member A2
  cell division cycle associated 8
  chondroitin sulfate N-acetylgalactosaminyltransferase 2
  chromosome 6 open reading frame 15
  CWC22 spliceosome associated protein homolog
  cytochrome b5 type B
  DnaJ heat shock protein family (Hsp40) member C5
  dynein axonemal assembly factor 2
  eukaryotic translation initiation factor 2B subunit beta
  eukaryotic translation initiation factor 2B subunit delta
  eukaryotic translation initiation factor 2B subunit epsilon
  eukaryotic translation initiation factor 2B subunit gamma
  golgi membrane protein 1
  GTPase, IMAP family member 5
  HCLS1 associated protein X-1
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  neurexin 1
  NSF attachment protein beta
  nuclear FMR1 interacting protein 1
  nuclear receptor subfamily 1 group H member 3
  RAB33A, member RAS oncogene family
  receptor for activated C kinase 1
  regulating synaptic membrane exocytosis 1
  ribosomal RNA processing 7 homolog A
  RNA binding motif protein 14
  SIN3 transcription regulator family member A
  stonin 2
  synaptic vesicle glycoprotein 2B
  synaptic vesicle glycoprotein 2C
  synaptotagmin 1
  synaptotagmin 2
  synaptotagmin 4
  synaptotagmin 5
  synaptotagmin binding cytoplasmic RNA interacting protein
  transcription factor AP-2 alpha
  transmembrane protein 14C
  transmembrane protein 254
  transmembrane protein 60
  UbiA prenyltransferase domain containing 1
  very low density lipoprotein receptor
  zinc finger DHHC-type palmitoyltransferase 17
  zinc finger protein like 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.