SERPINA5, serpin family A member 5

SERPINA5, serpin family A member 5

• The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. [provided by RefSeq, Aug 2012]

• Gene Synonyms (PAI-3, PAI3, PCI, PCI-B, PLANH3, PROCI, plasma serine protease inhibitor, acrosomal serine protease inhibitor, plasminogen activator inhibitor III, plasminogen activator inhibitor-3, protein C inhibitor, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5,)
• NCBI Gene ID: 5104
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DDH1
  UNIPROT ID#>>P05154
  UNIPROT ID#>>A0A024R6N9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serpin family A member 5 interacts with:

• COP9 signalosome subunit 6
  epithelial stromal interaction 1
  F-box protein 2
  HECT domain E3 ubiquitin protein ligase 3
  MIA SH3 domain ER export factor 3
  plasminogen activator, tissue type
  plasminogen activator, urokinase
  protein C, inactivator of coagulation factors Va and VIIIa
  protein inhibitor of activated STAT 4
  reactive intermediate imine deaminase A homolog
  ring finger and CHY zinc finger domain containing 1
  semenogelin 2
  serpin family A member 5
  thrombomodulin
  WW domain containing oxidoreductase
  zinc finger ZZ-type and EF-hand domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.