DNAJC10, DnaJ heat shock protein family (Hsp40) member C10

DNAJC10, DnaJ heat shock protein family (Hsp40) member C10

• This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces incorrect disulfide bonds in misfolded glycoproteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]

• Gene Synonyms (dnaJ homolog subfamily C member 10, DnaJ (Hsp40) homolog, subfamily C, member 10, ER-resident protein ERdj5, J-domain-containing protein disulfide isomerase-like protein, endoplasmic reticulum DNA J domain-containing protein 5, macrothioredoxin, protein disulfide isomerase family A, member 19, ERdj5, JPDI, MTHr, PDIA19,)
• NCBI Gene ID: 54431
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IXB1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DnaJ heat shock protein family (Hsp40) member C10 interacts with:

• centromere protein E
  C-type lectin domain containing 14A
  cullin associated and neddylation dissociated 1
  ER degradation enhancing alpha-mannosidase like protein 3
  FAD dependent oxidoreductase domain containing 2
  integrin alpha FG-GAP repeat containing 1
  MIS12 kinetochore complex component
  PGAM family member 5, mitochondrial serine/threonine protein phosphatase
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  PPARG coactivator 1 beta
  proprotein convertase subtilisin/kexin type 9
  SMAD specific E3 ubiquitin protein ligase 2
  tectonic family member 1
  trafficking protein particle complex 13
  translocase of outer mitochondrial membrane 22
  translocase of outer mitochondrial membrane 5
  unc-93 homolog B1, TLR signaling regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.