CHMP1B, charged multivesicular body protein 1B

CHMP1B, charged multivesicular body protein 1B

• CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (C10orf2, C18-ORF2, C18orf2, CHMP1.5, Vps46-2, Vps46B, hVps46-2, charged multivesicular body protein 1b, chromatin modifying protein 1B, chromatin-modifying protein 1b, vacuolar protein sorting 46-2, vacuolar protein sorting-associated protein 46-2,)
• NCBI Gene ID: 57132
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7LBR1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

charged multivesicular body protein 1B interacts with:

• charged multivesicular body protein 1B
  charged multivesicular body protein 4B
  charged multivesicular body protein 4B
  charged multivesicular body protein 4C
  kinetochore localized astrin (SPAG5) binding protein
  microtubule interacting and trafficking domain containing 1
  protein tyrosine phosphatase, non-receptor type 23
  RAB11 family interacting protein 1 (class I)
  RNF103-CHMP3 readthrough
  ubiquitin specific peptidase 54

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.