SOX9, SRY-box transcription factor 9

SOX9, SRY-box transcription factor 9

• The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008]

• Gene Synonyms (transcription factor SOX-9, SRY (sex determining region Y)-box9, SRY (sex-determining region Y)-box 9 protein, SRY-box 9, SRY-related HMG-box, gene 9, CMD1, CMPD1, SRA1, SRXX2, SRXY10,)
• NCBI Gene ID: 6662
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P48436
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SRY-box transcription factor 9 interacts with:

• ATPase H+ transporting V1 subunit H
  beta-transducin repeat containing E3 ubiquitin protein ligase
  cAMP responsive element binding protein 3 like 4
  F-box and WD repeat domain containing 7
  HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
  mediator complex subunit 12
  scleraxis bHLH transcription factor
  spen family transcriptional repressor
  SRY-box transcription factor 9
  TNF receptor associated factor 2
  ubiquitin conjugating enzyme E2 I
  vir like m6A methyltransferase associated
  zinc finger and BTB domain containing 7A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.