TAC3, tachykinin precursor 3

TAC3, tachykinin precursor 3

• This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded preproprotein is proteolytically processed to generate the mature peptide, which is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. This peptide is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

• Gene Synonyms (tachykinin-3, LncZBTB39-1:2, gamma tachykinin 3, neurokinin b, neuromedin K, preprotachykinin B, tachykinin 3, HH10, LncZBTB39, NK3, NKB, NKNB, PRO1155, ZNEUROK1,)
• NCBI Gene ID: 6866
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UHF0
  UNIPROT ID#>>A0A024RB97
  UNIPROT ID#>>A0A024RB47
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tachykinin precursor 3 interacts with:

• coiled-coil domain containing 90B
  elongator complex protein 1
  fasciculation and elongation protein zeta 1
  G protein-coupled receptor associated sorting protein 1
  tachykinin receptor 1
  tachykinin receptor 3
  ubiquitin C
  ubiquitin protein ligase E3 component n-recognin 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.