UBE2V2, ubiquitin conjugating enzyme E2 V2

UBE2V2, ubiquitin conjugating enzyme E2 V2

• Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ubiquitin-conjugating enzyme E2 variant 2, 1 alpha,25-dihydroxyvitamin D3-inducible, DDVit 1, MMS2 homolog, enterocyte differentiation promoting factor, enterocyte differentiation-associated factor 1, enterocyte differentiation-associated factor EDAF-1, enterocyte differentiation-promoting factor 1, methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of, vitamin D3-inducible protein, DDVIT1, DDVit-1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2,)
• NCBI Gene ID: 7336
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15819
  UNIPROT ID#>>A0M8W4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin conjugating enzyme E2 V2 interacts with:

• BCL10 immune signaling adaptor
  CD2 cytoplasmic tail binding protein 2
  complexin 1
  DAZ interacting zinc finger protein 3
  DNA polymerase kappa
  immunoglobin superfamily member 21
  ligand dependent nuclear receptor interacting factor 1
  ligand of numb-protein X 1
  makorin ring finger protein 3
  MALT1 paracaspase
  mitochondrial E3 ubiquitin protein ligase 1
  MOB family member 4, phocein
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  RANBP2-type and C3HC4-type zinc finger containing 1
  replication termination factor 2
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger and FYVE like domain containing E3 ubiquitin protein ligase
  ring finger protein 11
  ring finger protein 144A
  ring finger protein 8
  Sec23 homolog A, COPII coat complex component
  SNF2 histone linker PHD RING helicase
  STIP1 homology and U-box containing protein 1
  suppressor of variegation 3-9 homolog 2
  tetratricopeptide repeat domain 9C
  tigger transposable element derived 6
  TNFRSF1A associated via death domain
  tripartite motif containing 32
  tripartite motif containing 5
  tripartite motif containing 54
  tripartite motif containing 63
  tubulin tyrosine ligase like 12
  ubiquitin conjugating enzyme E2 M
  ubiquitin fold modifier 1
  ubiquitin specific peptidase 34
  ubiquitin specific peptidase 9 X-linked
  ubiquitin-conjugating enzyme E2N
  UBX domain protein 1
  UBX domain protein 7
  VPS26, retromer complex component A
  zinc and ring finger 1
  zinc finger FYVE-type containing 19
  zinc finger RANBP2-type containing 2
  zinc ribbon domain containing 2
  ZPR1 zinc finger
  zyxin

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.