ZBTB16, zinc finger and BTB domain containing 16

ZBTB16, zinc finger and BTB domain containing 16

• This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

• Gene Synonyms (zinc finger and BTB domain-containing protein 16, promyelocytic leukaemia zinc finger, zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia), zinc finger protein PLZF, PLZF, ZNF145,)
• NCBI Gene ID: 7704
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R3C6
  UNIPROT ID#>>Q05516
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc finger and BTB domain containing 16 interacts with:

• ADAM metallopeptidase with thrombospondin type 1 motif 4
  anaphase promoting complex subunit 5
  angiomotin like 2
  ATPase H+ transporting accessory protein 2
  basic leucine zipper nuclear factor 1
  caspase recruitment domain family member 9
  centrosomal protein 70
  centrosomal protein 72
  chromobox 5
  chromosome 16 open reading frame 70
  coenzyme Q6, monooxygenase
  coiled-coil alpha-helical rod protein 1
  coiled-coil domain containing 130
  coiled-coil domain containing 85B
  component of oligomeric golgi complex 6
  CTD small phosphatase 1
  dolichyl-phosphate mannosyltransferase subunit 1, catalytic
  dynein axonemal assembly factor 5
  ecto-NOX disulfide-thiol exchanger 1
  EF-hand domain containing 2
  epsin 1
  eukaryotic translation initiation factor 2 subunit beta
  family with sequence similarity 217 member B
  family with sequence similarity 90 member A1
  FCH and mu domain containing endocytic adaptor 1
  four and a half LIM domains 5
  glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
  golgin A6 family like 9
  G-patch domain and ankyrin repeats 1
  heat shock transcription factor 2 binding protein
  highly divergent homeobox
  histone deacetylase 3
  histone deacetylase 4
  histone deacetylase 5
  histone deacetylase 6
  histone deacetylase 7
  histone deacetylase 9
  homeobox A1
  interleukin 32
  keratin 40
  keratin associated protein 4-12
  late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
  LDOC1 regulator of NFKB signaling
  lemur tyrosine kinase 3
  leucine rich repeats and immunoglobulin like domains 1
  LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
  Ly1 antibody reactive
  metadherin
  metastasis associated 1 family member 2
  methyl-CpG binding domain protein 3
  microtubule associated scaffold protein 2
  midline 2
  mitochondrial calcium uniporter dominant negative subunit beta
  myosin regulatory light chain interacting protein
  NFKB inhibitor delta
  NLR family pyrin domain containing 7
  nuclear receptor corepressor 1
  nuclear receptor corepressor 2
  oxysterol binding protein like 3
  PGAM family member 5, mitochondrial serine/threonine protein phosphatase
  progesterone immunomodulatory binding factor 1
  proline rich nuclear receptor coactivator 2
  protein inhibitor of activated STAT 2
  queuine tRNA-ribosyltransferase catalytic subunit 1
  RAB3A interacting protein
  RAD50 interactor 1
  refilin B
  ring finger protein 112
  SH2 domain containing 4A
  SIN3 transcription regulator family member A
  SIN3 transcription regulator family member B
  speckle type BTB/POZ protein
  sprouty RTK signaling antagonist 2
  tetratricopeptide repeat domain 23
  TGF-beta activated kinase 1 (MAP3K7) binding protein 2
  thioredoxin interacting protein
  threonine synthase like 2
  TNF receptor associated factor 4
  toll interacting protein
  trans-acting transcription factor 1
  tripartite motif containing 54
  tyrosine kinase non receptor 2
  vesicle trafficking 1
  WASH complex subunit 1
  WD repeat domain 33
  zinc finger and BTB domain containing 16
  zinc finger and BTB domain containing 32
  zinc finger and BTB domain containing 42
  zinc finger protein 281
  zinc finger protein 552
  zinc finger protein 620
  zinc finger protein 655

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.