SLC25A12, solute carrier family 25 member 12

SLC25A12, solute carrier family 25 member 12

• This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]

• Gene Synonyms (calcium-binding mitochondrial carrier protein Aralar1, araceli hiperlarga, calcium binding mitochondrial carrier superfamily member Aralar1, mitochondrial aspartate glutamate carrier 1, solute carrier family 25 (aspartate/glutamate carrier), member 12, solute carrier family 25 (mitochondrial carrier, Aralar), member 12, AGC1, ARALAR, EIEE39,)
• NCBI Gene ID: 8604
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75746
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier family 25 member 12 interacts with:

• A-kinase anchoring protein 5
  apoptosis associated tyrosine kinase
  apoptosis inducing factor mitochondria associated 1
  autophagy related 16 like 1
  bromodomain containing 7
  centrosomal protein 128
  centrosomal protein 89
  coiled-coil-helix-coiled-coil-helix domain containing 6
  cytochrome c oxidase assembly factor COX14
  egl-9 family hypoxia inducible factor 3
  F-box protein 6
  glutamate rich WD repeat containing 1
  huntingtin
  hypoxia inducible factor 1 subunit alpha inhibitor
  inner membrane mitochondrial protein
  limb development membrane protein 1 like
  nicastrin
  nicotinamide nucleotide transhydrogenase
  pelota mRNA surveillance and ribosome rescue factor
  platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
  pleckstrin homology domain containing A4
  pleckstrin homology like domain family A member 3
  polynucleotide kinase 3'-phosphatase
  proprotein convertase subtilisin/kexin type 9
  RAB5 interacting factor
  receptor interacting serine/threonine kinase 4
  RecQ like helicase 4
  sideroflexin 1
  SLIT-ROBO Rho GTPase activating protein 2
  solute carrier family 25 member 13
  synaptojanin 2 binding protein
  TBC1 domain containing kinase
  TPX2, microtubule-associated
  transmembrane 9 superfamily member 4
  tripartite motif containing 28
  VAMP associated protein A
  WW domain containing oxidoreductase
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.