TBPL1, TATA-box binding protein like 1

TBPL1, TATA-box binding protein like 1

• This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Nov 2011]

• Gene Synonyms (TATA box-binding protein-like protein 1, 21-kDA TBP-like protein, TATA box-binding protein-related factor 2, TBP-like 1, TBP-related factor 2, TBP-related protein, second TBP of unique DNA protein, MGC:8389, MGC:9620, STUD, TLF, TLP, TRF2,)
• NCBI Gene ID: 9519
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P62380
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TATA-box binding protein like 1 interacts with:

• ATP binding cassette subfamily F member 3
  F-box protein 7
  interleukin 1 receptor associated kinase 4
  LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
  pentatricopeptide repeat domain 3
  perilipin 3
  phosphomevalonate kinase
  pleckstrin homology domain containing A4
  RAB35, member RAS oncogene family
  solute carrier family 35 member F6
  TATA-box binding protein associated factor 1 like
  TATA-box binding protein like 2
  tripartite motif containing 28

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.