IST1, IST1 factor associated with ESCRT-III

IST1, IST1 factor associated with ESCRT-III

• This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

• Gene Synonyms (IST1 homolog, IST1, ESCRT-III associated factor, IST1, endosomal sorting complex required for transport-III component, increased sodium tolerance 1 homolog, overexpressed in lung cancer 1, putative MAPK-activating protein PM28, CHMP8, OLC1,)
• NCBI Gene ID: 9798
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P53990
  UNIPROT ID#>>B4DXC9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

IST1 factor associated with ESCRT-III interacts with:

• anaphase promoting complex subunit 2
  ATPase H+ transporting accessory protein 2
  basic transcription factor 3 like 4
  BICD cargo adaptor 2
  bone morphogenetic protein receptor, type 1A
  calpain 7
  CCR4-NOT transcription complex, subunit 2
  CD2-associated protein
  centrosomal protein 55
  charged multivesicular body protein 1B
  charged multivesicular body protein 4B
  charged multivesicular body protein 4B
  cyclic GMP-AMP synthase
  endoplasmic reticulum-golgi intermediate compartment 1
  fizzy and cell division cycle 20 related 1
  golgi transport 1B
  hes related family bHLH transcription factor with YRPW motif 2
  IQ motif containing GTPase activating protein 3
  mindbomb E3 ubiquitin protein ligase 2
  myosin, light chain 12A, regulatory, non-sarcomeric
  pleckstrin homology domain containing A4
  protein prenyltransferase alpha subunit repeat containing 1
  protein tyrosine phosphatase, non-receptor type 23
  spastin
  TOX high mobility group box family member 3
  trafficking from ER to golgi regulator
  translocase of inner mitochondrial membrane 13
  transmembrane p24 trafficking protein 2
  tumor susceptibility gene 101
  ubiquilin 1
  ubiquilin 2
  ubiquitin specific peptidase 47
  vacuolar protein sorting 4 homolog A
  vacuolar protein sorting 4B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.