MRPL28, mitochondrial ribosomal protein L28

MRPL28, mitochondrial ribosomal protein L28

• Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008]

• Gene Synonyms (MAAT1, p15, 39S ribosomal protein L28, mitochondrial, L28mt, MRP-L28, melanoma antigen p15, melanoma-associated antigen recognised by cytotoxic T lymphocytes, melanoma-associated antigen recognized by T-lymphocytes, mitochondrial large ribosomal subunit protein bL28m,)
• NCBI Gene ID: 10573
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13084
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitochondrial ribosomal protein L28 interacts with:

• adipocyte plasma membrane associated protein
  aurora kinase A interacting protein 1
  BTG3 associated nuclear protein
  cell division cycle associated 7 like
  centrosomal protein 72
  enkurin domain containing 1
  family with sequence similarity 9 member B
  GADD45G interacting protein 1
  homeobox containing 1
  IKAROS family zinc finger 3
  La ribonucleoprotein 1B
  leucine rich repeat kinase 2
  leukocyte receptor cluster member 1
  listerin E3 ubiquitin protein ligase 1
  mitochondrial assembly of ribosomal large subunit 1
  mitochondrial ribosomal protein L1
  mitochondrial ribosomal protein L10
  mitochondrial ribosomal protein L13
  mitochondrial ribosomal protein L14
  mitochondrial ribosomal protein L15
  mitochondrial ribosomal protein L16
  mitochondrial ribosomal protein L17
  mitochondrial ribosomal protein L2
  mitochondrial ribosomal protein L20
  mitochondrial ribosomal protein L22
  mitochondrial ribosomal protein L24
  mitochondrial ribosomal protein L27
  mitochondrial ribosomal protein L3
  mitochondrial ribosomal protein L30
  mitochondrial ribosomal protein L32
  mitochondrial ribosomal protein L34
  mitochondrial ribosomal protein L35
  mitochondrial ribosomal protein L37
  mitochondrial ribosomal protein L38
  mitochondrial ribosomal protein L39
  mitochondrial ribosomal protein L4
  mitochondrial ribosomal protein L40
  mitochondrial ribosomal protein L41
  mitochondrial ribosomal protein L42
  mitochondrial ribosomal protein L44
  mitochondrial ribosomal protein L45
  mitochondrial ribosomal protein L46
  mitochondrial ribosomal protein L47
  mitochondrial ribosomal protein L50
  mitochondrial ribosomal protein L55
  mitochondrial ribosomal protein L57
  mitochondrial ribosomal protein L9
  mitochondrial ribosomal protein S18A
  mitochondrial ribosomal protein S30
  mitochondrial ribosomal protein S7
  mitochondrial rRNA methyltransferase 1
  mitochondrial rRNA methyltransferase 3
  NFKB inhibitor delta
  SERPINE1 mRNA binding protein 1
  sodium channel modifier 1
  teashirt zinc finger homeobox 3
  testis specific serine kinase 3
  TRAF3 interacting protein 2
  tRNA methyltransferase 61B
  ubiquitin specific peptidase 20
  uridine phosphorylase 2
  zinc finger protein 331
  zinc finger protein 655

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.