EHMT2, euchromatic histone lysine methyltransferase 2

EHMT2, euchromatic histone lysine methyltransferase 2

• This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

• Gene Synonyms (BAT8, C6orf30, G9A, GAT8, KMT1C, NG36, histone-lysine N-methyltransferase EHMT2, G9A histone methyltransferase, H3-K9-HMTase 3, HLA-B associated transcript 8, ankyrin repeat-containing protein, euchromatic histone-lysine N-methyltransferase 2, histone H3-K9 methyltransferase 3, histone-lysine N-methyltransferase, H3 lysine-9 specific 3, lysine N-methyltransferase 1C,)
• NCBI Gene ID: 10919
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RCN9
  UNIPROT ID#>>Q96KQ7
  UNIPROT ID#>>Q59FM7
  UNIPROT ID#>>A2ABF8
  UNIPROT ID#>>B7Z852
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

euchromatic histone lysine methyltransferase 2 interacts with:

• abhydrolase domain containing 17A, depalmitoylase
  activating transcription factor 7 interacting protein
  BUB1, mitotic checkpoint serine/threonine kinase
  catenin alpha 3
  chromobox 1
  chromobox 1
  chromobox 3
  chromobox 5
  coiled-coil domain containing 33
  coiled-coil-helix-coiled-coil-helix domain containing 2
  ependymin related 1
  establishment of sister chromatid cohesion N-acetyltransferase 1
  establishment of sister chromatid cohesion N-acetyltransferase 2
  euchromatic histone lysine methyltransferase 1
  euchromatic histone lysine methyltransferase 2
  euchromatic histone methyltransferase 1
  FAM161 centrosomal protein A
  F-box protein 38
  glutamate receptor interacting protein 1
  H2B clustered histone 1
  H3 clustered histone 14
  H3 clustered histone 15
  heterogeneous nuclear ribonucleoprotein F
  HIC ZBTB transcriptional repressor 2
  Kruppel like factor 12
  Kruppel like factor 3
  L3MBTL histone methyl-lysine binding protein 1
  lacritin
  leucine rich repeats and WD repeat domain containing 1
  ligand dependent nuclear receptor corepressor
  ligand of numb-protein X 1
  ligase I, DNA, ATP-dependent
  LIM homeobox 6
  lysine demethylase 1B
  MAD2 mitotic arrest deficient-like 2
  Max protein
  mediator complex subunit 30
  MIER family member 2
  MIER1 transcriptional regulator
  N-acetylglucosamine kinase
  N-alpha-acetyltransferase 11, NatA catalytic subunit
  nicotinate phosphoribosyltransferase
  PR/SET domain 5
  proline rich coiled-coil 2B
  protein phosphatase 4 regulatory subunit 3A
  retinal degeneration 3, GUCY2D regulator
  RPTOR independent companion of MTOR complex 2
  sirtuin 6
  solute carrier family 16 member 8
  suppressor of variegation 3-9 homolog 2
  SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
  THAP domain containing 7
  tropomyosin 4
  ubiquitin like with PHD and ring finger domains 1
  ubiquitin like with PHD and ring finger domains 2
  WD repeat domain 5
  widely-interspaced zinc finger motifs
  WIZ zinc finger
  X antigen family member 3
  zinc finger and BTB domain containing 38
  zinc finger and BTB domain containing 46
  zinc finger and BTB domain containing 7A
  zinc finger protein 446
  zinc finger protein 462
  zinc finger protein 512B
  zinc finger protein 644
  zinc finger protein 688
  zinc finger protein 775
  zinc finger protein 785
  zinc finger protein 837

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.