COPE, COPI coat complex subunit epsilon

COPE, COPI coat complex subunit epsilon

• The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (coatomer subunit epsilon, coatomer epsilon subunit, coatomer protein complex subunit epsilon, epsilon coat protein, epsilon-COP,)
• NCBI Gene ID: 11316
• Species: Homo sapiens (Human)
• UNIPROT ID#>>M0QXB4
  UNIPROT ID#>>O14579
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

COPI coat complex subunit epsilon interacts with:

• 5'-3' exoribonuclease 1
  BCL2 like 14
  coatomer protein complex subunit alpha
  COPI coat complex subunit epsilon
  COPI coat complex subunit gamma 1
  COPI coat complex subunit gamma 2
  COPI coat complex subunit zeta 1
  crystallin lambda 1
  cytochrome c oxidase assembly factor COX14
  developmental pluripotency-associated 3
  DIMT1 rRNA methyltransferase and ribosome maturation factor
  dynactin subunit 5
  dystrobrevin binding protein 1
  EF-hand domain containing 2
  endoplasmic reticulum protein 44
  family with sequence similarity 210 member A
  G protein subunit gamma 12
  G protein-coupled receptor associated sorting protein 2
  glutaminyl-peptide cyclotransferase like
  integrin alpha FG-GAP repeat containing 1
  inverted formin 2
  katanin p60 (ATPase-containing) subunit A1
  MDM2 binding protein
  mitochondrial ribosomal protein L22
  multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
  NudC domain containing 1
  oxysterol binding protein like 9
  PAX interacting protein 1
  peptidyl-tRNA hydrolase 2
  phosphoserine aminotransferase 1
  pleckstrin homology domain containing A4
  PR/SET domain 16
  RAB GTPase activating protein 1
  ring finger and CHY zinc finger domain containing 1
  ring finger protein 213
  SAC1 like phosphatidylinositide phosphatase
  SAC1 suppressor of actin mutations 1-like (yeast)
  Sad1 and UNC84 domain containing 2
  SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
  SCY1 like pseudokinase 1
  solute carrier family 15 member 3
  splicing factor 3b subunit 3
  splicing factor 3b subunit 5
  sulfotransferase family 1C member 4
  tectonic family member 3
  TNFAIP3 interacting protein 2
  transmembrane protein 17
  tubulin beta class I
  tubulin gamma complex associated protein 4
  unc-93 homolog B1, TLR signaling regulator
  vacuolar protein sorting 4 homolog A
  vir like m6A methyltransferase associated
  WD repeat domain 7
  WD repeat domain, phosphoinositide interacting 2
  WW domain binding protein 2
  zinc finger protein 511
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.