MST1, macrophage stimulating 1

MST1, macrophage stimulating 1

• The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds. [provided by RefSeq, Jan 2010]

• Gene Synonyms (D3F15S2, DNF15S2, HGFL, MSP, NF15S2, hepatocyte growth factor-like protein, hepatocyte growth factor-like protein homolog, macrophage stimulating 1 (hepatocyte growth factor-like), macrophage-stimulating protein,)
• NCBI Gene ID: 4485
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P26927
  UNIPROT ID#>>Q53GN8
  UNIPROT ID#>>G3XAK1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

macrophage stimulating 1 interacts with:

• beclin 1
  macrophage stimulating 1
  macrophage stimulating 1 receptor
  MOB kinase activator 1A
  protein phosphatase, Mg2+/Mn2+ dependent 1F
  Ras association domain family member 1
  ring finger protein 123
  troponin C1, slow skeletal and cardiac type
  troponin I3, cardiac type
  troponin T2, cardiac type

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.