PSPH, phosphoserine phosphatase

PSPH, phosphoserine phosphatase

• The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008]

• Gene Synonyms (phosphoserine phosphatase, L-3-phosphoserine phosphatase, O-phosphoserine phosphohydrolase, PSPase, PSP, PSPHD,)
• NCBI Gene ID: 5723
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P78330
  UNIPROT ID#>>A0A024RDL3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphoserine phosphatase interacts with:

• anti-silencing function 1B histone chaperone
  ataxin 1
  CCR4-NOT transcription complex subunit 1
  exosome component 2
  flavin adenine dinucleotide synthetase 1
  O-linked N-acetylglucosamine (GlcNAc) transferase
  phosphoglycerate dehydrogenase
  phosphoserine phosphatase
  serine/threonine/tyrosine interacting like 1
  SHC adaptor protein 1
  small nuclear RNA activating complex polypeptide 1
  translocase of inner mitochondrial membrane 8 homolog B
  tripartite motif containing 25
  tumor protein p63
  ubiquitin like modifier activating enzyme 2
  vacuolar protein sorting 72 homolog
  WD repeat domain 61
  zinc finger matrin-type 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.