RCN2, reticulocalbin 2

RCN2, reticulocalbin 2

• The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]

• Gene Synonyms (reticulocalbin-2, E6-binding protein, calcium-binding protein ERC-55, reticulocalbin 2, EF-hand calcium binding domain (endoplasmic reticulum calcium-binding protein, 55kD), E6BP, ERC-55, ERC55, TCBP49,)
• NCBI Gene ID: 5955
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14257
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

reticulocalbin 2 interacts with:

• ankyrin repeat and SOCS box containing 12
  ankyrin repeat and SOCS box containing 17
  ankyrin repeat and SOCS box containing 3
  ankyrin repeat domain 28
  ariadne RBR E3 ubiquitin protein ligase 2
  armadillo repeat containing X-linked 3
  assembly factor for spindle microtubules
  autophagy and beclin 1 regulator 1
  BAG cochaperone 6
  bromodomain containing 7
  calreticulin 3
  caseinolytic mitochondrial matrix peptidase proteolytic subunit
  centrosomal protein 250
  centrosomal protein 76
  chromobox 1
  chromobox 3
  chromobox 5
  coronin 1C
  cullin 3
  DExD/H-box helicase 60
  dual specificity phosphatase 16
  Ecm29 proteasome adaptor and scaffold
  egl-9 family hypoxia inducible factor 3
  EP300 interacting inhibitor of differentiation 1
  ER membrane protein complex subunit 2
  ER membrane protein complex subunit 8
  euchromatic histone lysine methyltransferase 2
  exportin 1
  family with sequence similarity 210 member A
  FERM domain containing 5
  FKBP prolyl isomerase 10
  FKBP prolyl isomerase 9
  GABA type A receptor associated protein like 1
  GABA type A receptor associated protein like 2
  HAUS augmin like complex subunit 2
  histone deacetylase 11
  hook microtubule tethering protein 3
  insulin receptor substrate 4
  integrin alpha FG-GAP repeat containing 1
  IQ motif containing B1
  kinase suppressor of ras 1
  La ribonucleoprotein 7, transcriptional regulator
  lactamase beta
  large tumor suppressor kinase 2
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat containing 59
  lon peptidase 1, mitochondrial
  MAD2 mitotic arrest deficient-like 2
  malignant fibrous histiocytoma amplified sequence 1
  NADH:ubiquinone oxidoreductase core subunit S7
  nicotinamide nucleotide transhydrogenase
  nipsnap homolog 1
  peroxiredoxin 4
  PHD finger protein 19
  poly(A) specific ribonuclease subunit PAN2
  PR/SET domain 16
  RecQ like helicase 4
  ring finger and CCCH-type domains 2
  ring-box 1
  sequestosome 1
  serine/threonine kinase 40
  sideroflexin 1
  snail family transcriptional repressor 1
  solute carrier family 15 member 3
  solute carrier family 2 member 3
  solute carrier family 25 member 24
  spermatogenesis associated 5
  SprT-like N-terminal domain
  stromal cell derived factor 4
  tectonic family member 1
  tectonic family member 3
  TNFAIP3 interacting protein 2
  transcription factor Dp-1
  tripartite motif-containing 28
  Tu translation elongation factor, mitochondrial
  tubulin alpha 1c
  tubulin gamma complex associated protein 3
  tumor protein p53
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  ubiquinol-cytochrome c reductase core protein 2
  ubiquinol-cytochrome c reductase hinge protein
  ubiquitin conjugating enzyme E2 M
  unc-93 homolog B1, TLR signaling regulator
  valosin containing protein
  vir like m6A methyltransferase associated
  voltage dependent anion channel 1
  zinc finger protein 217
  zinc finger protein 462

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.