THRA, thyroid hormone receptor alpha

THRA, thyroid hormone receptor alpha

• The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

• Gene Synonyms (thyroid hormone receptor alpha, EAR-7, ERBA-related 7, V-erbA-related protein 7, c-erbA-alpha, nuclear receptor subfamily 1 group A member 1, thyroid hormone receptor alpha 1, thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian), thyroid normone nuclear receptor alpha variant 1, triiodothyronine receptor, AR7, CHNG6, EAR7, ERB-T-1, ERBA, ERBA1, NR1A1, THRA1, THRA2, c-ERBA-1,)
• NCBI Gene ID: 7067
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6FH41
  UNIPROT ID#>>P10827
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

thyroid hormone receptor alpha interacts with:

• 2'-5'-oligoadenylate synthetase like
  A-kinase anchoring protein 13
  alpha-2-macroglobulin like 1
  angiomotin like 2
  AT-rich interaction domain 5A
  BUB3 mitotic checkpoint protein
  C1D nuclear receptor corepressor
  CD160 molecule
  centrosomal protein 76
  COP9 signalosome subunit 2
  cullin 1
  death associated protein 3
  glutamate receptor interacting protein 1
  histone deacetylase 2
  histone deacetylase 3
  HR lysine demethylase and nuclear receptor corepressor
  integrin subunit beta 3 binding protein
  L3MBTL histone methyl-lysine binding protein 3
  mediator complex subunit 12
  mediator complex subunit 14
  mediator complex subunit 16
  mediator complex subunit 17
  mediator complex subunit 21
  mediator complex subunit 24
  mediator complex subunit 25
  mediator complex subunit 6
  nuclear receptor binding SET domain protein 1
  nuclear receptor coactivator 1
  nuclear receptor coactivator 2
  nuclear receptor coactivator 3
  nuclear receptor coactivator 6
  nuclear receptor corepressor 1
  nuclear receptor corepressor 2
  nuclear receptor interacting protein 1
  nuclear receptor subfamily 0 group B member 2
  nuclear receptor subfamily 0, group B, member 2
  nuclear receptor-binding SET-domain protein 1
  nuclear RNA export factor 1
  prostaglandin E synthase 3
  RAN binding protein 9
  regucalcin
  structural maintenance of chromosomes 1A
  synapse associated protein 1
  TBL1X receptor 1
  thioredoxin reductase 1
  thyroid hormone receptor alpha
  thyroid hormone receptor associated protein 3
  thyroid hormone receptor interactor 11
  tripartite motif containing 24
  tripartite motif containing 63
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  ubiquitin conjugating enzyme E2 I
  X-ray repair cross complementing 5
  zinc finger and BTB domain containing 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.