TIAL1, TIA1 cytotoxic granule associated RNA binding protein like 1

TIAL1, TIA1 cytotoxic granule associated RNA binding protein like 1

• The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq, Jul 2008]

• Gene Synonyms (nucleolysin TIAR, T-cluster binding protein, TIA-1-related nucleolysin, TIA1 related, aging-associated gene 7 protein, TCBP, TIAR,)
• NCBI Gene ID: 7073
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q49AS9
  UNIPROT ID#>>Q01085
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TIA1 cytotoxic granule associated RNA binding protein like 1 interacts with:

• acetyl-CoA acyltransferase 2
  A-kinase anchoring protein 8 like
  aldehyde dehydrogenase 5 family member A1
  BPI fold containing family A member 1
  coactosin like F-actin binding protein 1
  coiled-coil domain containing 58
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  CUGBP Elav-like family member 4
  cullin 1
  cullin 2
  cullin 3
  cullin 4A
  cullin 4B
  cullin 5
  cullin 7
  cullin associated and neddylation dissociated 1
  DAZ associated protein 1
  DAZ associated protein 2
  DAZ interacting zinc finger protein 3
  defective in cullin neddylation 1 domain containing 1
  exportin 1
  family with sequence similarity 168 member A
  family with sequence similarity 168 member B
  family with sequence similarity 83 member H
  far upstream element binding protein 1
  G3BP stress granule assembly factor 1
  inhibitor of CDK, cyclin A1 interacting protein 1
  internexin neuronal intermediate filament protein alpha
  kelch repeat and BTB domain containing 7
  keratin associated protein 8-1
  Kruppel like factor 1
  MAGE family member D1
  mitochondrial ribosomal protein L53
  mitochondrial ribosomal protein S28
  mitogen-activated protein kinase 1 interacting protein 1 like
  muscleblind like splicing regulator 2
  Nanog homeobox
  obscurin like cytoskeletal adaptor 1
  OTU deubiquitinase 4
  peptidyl-tRNA hydrolase domain containing 1
  pirin
  pleckstrin homology domain containing A4
  polycomb group ring finger 1
  proline rich 13
  proline rich 20A
  proline rich 20B
  proline rich 20C
  proline rich 20D
  proline rich 20E
  protein phosphatase 6, regulatory subunit 1
  QKI, KH domain containing RNA binding
  RAB10, member RAS oncogene family
  receptor for activated C kinase 1
  RNA binding protein, mRNA processing factor 2
  salvador family WW domain containing protein 1
  SAP domain containing ribonucleoprotein
  SBDS ribosome maturation factor
  secretory carrier membrane protein 3
  splicing factor 3b subunit 4
  synthesis of cytochrome C oxidase 2
  translocase of outer mitochondrial membrane 40
  tripartite motif containing 25
  tripartite motif containing 28
  trophinin
  ubiquitin conjugating enzyme E2 D2
  ubiquitin fold modifier 1
  vascular cell adhesion molecule 1
  voltage dependent anion channel 1
  VPS37C subunit of ESCRT-I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.