TKT, transketolase

TKT, transketolase

• This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]

• Gene Synonyms (transketolase, epididymis luminal protein 107, epididymis secretory protein Li 48, HEL-S-48, HEL107, SDDHD, TK, TKT1,)
• NCBI Gene ID: 7086
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0B4J1R6
  UNIPROT ID#>>P29401
  UNIPROT ID#>>V9HWD9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transketolase interacts with:

• AAR2 splicing factor
  abhydrolase domain containing 14B
  acetyl-CoA acyltransferase 2
  adenosylhomocysteinase like 1
  AKT interacting protein
  aldehyde dehydrogenase 4 family member A1
  aldo-keto reductase family 1 member A1
  aldo-keto reductase family 1 member B15
  aminoadipate-semialdehyde dehydrogenase
  anterior gradient 2, protein disulphide isomerase family member
  autophagy related 2B
  autophagy related 5
  BCL6 corepressor
  casein kinase 1, epsilon
  CDK5 regulatory subunit associated protein 2
  chromosome 11 open reading frame 54
  chromosome 5 open reading frame 34
  coactosin like F-actin binding protein 1
  coenzyme Q2, polyprenyltransferase
  cullin 3
  cytochrome c oxidase copper chaperone COX17
  DAZ associated protein 1
  destrin, actin depolymerizing factor
  dipeptidyl peptidase 9
  DNA polymerase alpha 2, accessory subunit
  dynamin 1 like
  dynein cytoplasmic 1 light intermediate chain 1
  elongation factor Tu GTP binding domain containing 2
  EMAP like 4
  eukaryotic translation initiation factor 2 alpha kinase 4
  expressed sequence AI837181
  ezrin
  F-box protein 6
  fidgetin like 1
  FKBP prolyl isomerase 7
  glyoxalase domain containing 4
  growth regulating estrogen receptor binding 1
  H2A clustered histone 4
  H4 clustered histone 1
  heat shock protein family A (Hsp70) member 4 like
  histone deacetylase 5
  ISG15 ubiquitin like modifier
  KH and NYN domain containing
  lactate dehydrogenase A like 6B
  leucine aminopeptidase 3
  leucine carboxyl methyltransferase 2
  leucine rich repeat kinase 2
  lysine demethylase 5C
  lysophospholipase 2
  mediator complex subunit 17
  mediator complex subunit 20
  mitogen-activated protein kinase kinase kinase 13
  molybdenum cofactor sulfurase
  N-acetylneuraminate synthase
  NADH:ubiquinone oxidoreductase complex assembly factor 3
  NHL repeat containing 2
  NME1-NME2 readthrough
  nuclear receptor subfamily 2 group C member 2
  phosphatidylinositol transfer protein beta
  phosphoethanolamine/phosphocholine phosphatase 1
  phosphoglucomutase 2
  phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
  PIH1 domain containing 1
  pirin
  pleckstrin homology domain containing A4
  potassium channel tetramerization domain containing 10
  POTE ankyrin domain family member F
  programmed cell death 6
  programmed cell death 6 interacting protein
  prostaglandin E synthase 3
  protein phosphatase methylesterase 1
  PTEN induced kinase 1
  RAB10, member RAS oncogene family
  RecQ like helicase 4
  regulatory associated protein of MTOR complex 1
  ribose 5-phosphate isomerase A
  SCY1 like pseudokinase 2
  sequestosome 1
  SMG8 nonsense mediated mRNA decay factor
  solute carrier family 2 member 9
  SPC25 component of NDC80 kinetochore complex
  splicing factor 1
  stress induced phosphoprotein 1
  striatin, calmodulin binding protein 3
  TBC1 domain family member 4
  testin LIM domain protein
  TP53 induced glycolysis regulatory phosphatase
  trafficking protein particle complex 8
  transgelin 2
  transgelin 3
  transketolase
  triosephosphate isomerase 1
  tripartite motif containing 32
  tubulin alpha 4a
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin conjugating enzyme E2 D1
  ubiquitin conjugating enzyme E2 I
  ubiquitin conjugating enzyme E2 M
  ubiquitin fold modifier 1
  ubiquitin-fold modifier conjugating enzyme 1
  UDP-glucose 6-dehydrogenase
  valosin containing protein
  VAMP associated protein A
  vir like m6A methyltransferase associated
  voltage dependent anion channel 1
  voltage dependent anion channel 3
  WD repeat domain 1
  WD repeat domain 19
  WD repeat domain 41
  WD repeat domain 54
  Yes1 associated transcriptional regulator
  YKT6 v-SNARE homolog
  zinc finger protein 598, E3 ubiquitin ligase
  zinc ribbon domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.