URI1, URI1 prefoldin like chaperone

URI1, URI1 prefoldin like chaperone

• This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22. [provided by RefSeq, Nov 2011]

• Gene Synonyms (unconventional prefoldin RPB5 interactor 1, RNA polymerase II subunit 5-mediating protein, RPB5-mediating protein, protein phosphatase 1, regulatory subunit 19, C19orf2, NNX3, PPP1R19, RMP, URI,)
• NCBI Gene ID: 8725
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O94763
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

URI1 prefoldin like chaperone interacts with:

• activating transcription factor 7
  ankyrin repeat and SOCS box containing 7
  cytosolic iron-sulfur assembly component 1
  DNA methyltransferase 1 associated protein 1
  DnaJ heat shock protein family (Hsp40) member A2
  egl-9 family hypoxia inducible factor 3
  GPN-loop GTPase 1
  GPN-loop GTPase 3
  HECT and RLD domain containing E3 ubiquitin protein ligase 2
  itchy E3 ubiquitin protein ligase
  NOP58 ribonucleoprotein
  nucleolar complex associated 4 homolog
  p53 and DNA damage regulated 1
  PIH1 domain containing 1
  plakophilin 3
  prefoldin 2
  prefoldin subunit 6
  pre-mRNA processing factor 8
  proteasome 26S subunit, non-ATPase 14
  RecQ like helicase 4
  regulation of nuclear pre-mRNA domain containing 1B
  RNA polymerase I and III subunit C
  RNA polymerase I and III subunit D
  RNA polymerase I subunit A
  RNA polymerase II associated protein 2
  RNA polymerase II associated protein 3
  RNA polymerase III subunit A
  RNA polymerase III subunit B
  RNA polymerase III subunit E
  RuvB like AAA ATPase 2
  RuvB-like protein 1
  RuvB-like protein 2
  septin 9
  signal transducing adaptor family member 1
  TBC1 domain family member 7
  TELO2 interacting protein 1
  transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
  transport and golgi organization 6 homolog
  tripartite motif containing 28
  URI1 prefoldin like chaperone
  vir like m6A methyltransferase associated
  WD repeat domain 77
  WD repeat domain 92
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger B-box domain containing
  zinc finger CCCH-type containing, antiviral 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.