UBE2W, ubiquitin conjugating enzyme E2 W

UBE2W, ubiquitin conjugating enzyme E2 W

• This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

• Gene Synonyms (UBC-16, UBC16, ubiquitin-conjugating enzyme E2 W, E2 ubiquitin-conjugating enzyme W, N-terminal E2 ubiquitin-conjugating enzyme, N-terminus-conjugating E2, ubiquitin carrier protein W, ubiquitin conjugating enzyme E2 W (putative), ubiquitin conjugating enzyme E2W (putative), ubiquitin-conjugating enzyme 16, ubiquitin-conjugating enzyme 2W, ubiquitin-protein ligase W,)
• NCBI Gene ID: 55284
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96B02
  UNIPROT ID#>>Q96FI0
  UNIPROT ID#>>X6REH9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin conjugating enzyme E2 W interacts with:

• calcium dependent secretion activator 2
  checkpoint with forkhead and ring finger domains
  deltex E3 ubiquitin ligase 3
  deltex E3 ubiquitin ligase 3L
  leucine rich repeat and sterile alpha motif containing 1
  membrane associated ring-CH-type finger 3
  mindbomb E3 ubiquitin protein ligase 1
  mitochondrial E3 ubiquitin protein ligase 1
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  required for meiotic nuclear division 5 homolog B
  ring finger protein 114
  ring finger protein 123
  ring finger protein 150
  ring finger protein 152
  ring finger protein 165
  ring finger protein 166
  ring finger protein 183
  ring finger protein 185
  ring finger protein 26
  tripartite motif containing 39
  tripartite motif containing 5
  tripartite motif containing 59
  tripartite motif containing 8
  ubiquitin conjugating enzyme E2 W
  ubiquitin like with PHD and ring finger domains 2
  ubiquitination factor E4B
  USH1 protein network component harmonin binding protein 1
  zinc and ring finger 1
  zinc and ring finger 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.