VTN, vitronectin

VTN, vitronectin

• The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008]

• Gene Synonyms (vitronectin, complement S-protein, epibolin, serum spreading factor, somatomedin B, V75, VN, VNT,)
• NCBI Gene ID: 7448
• Species: Homo sapiens (Human)
• UNIPROT ID#>>D9ZGG2
  UNIPROT ID#>>P04004
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

vitronectin interacts with:

• 3-hydroxyacyl-CoA dehydratase 2
  androgen dependent TFPI regulating protein
  armadillo repeat containing X-linked 3
  BUD31 homolog
  CASP2 and RIPK1 domain containing adaptor with death domain
  chromobox 1
  COP9 signalosome subunit 5
  cullin 7
  cullin 9
  DDB1 and CUL4 associated factor 1
  DEK proto-oncogene
  embryonic ectoderm development
  ETS variant transcription factor 7
  FAST kinase domains 3
  F-box protein 33
  G protein regulated inducer of neurite outgrowth 1
  golgi associated PDZ and coiled-coil motif containing
  heterochromatin protein 1 binding protein 3
  heterogeneous nuclear ribonucleoprotein R
  histone acetyltransferase 1
  integrin subunit alpha 8
  isochorismatase domain containing 1
  lacritin
  LEM domain nuclear envelope protein 2
  ligand of numb-protein X 2
  LUC7 like 3 pre-mRNA splicing factor
  lysophosphatidylcholine acyltransferase 3
  magnesium transporter MRS2
  myosin phosphatase Rho interacting protein
  OTU deubiquitinase 4
  pentatricopeptide repeat domain 2
  peroxiredoxin 4
  phosphoglycerate dehydrogenase
  POP1 homolog, ribonuclease P/MRP subunit
  POP4 homolog, ribonuclease P/MRP subunit
  pre-mRNA processing factor 19
  pre-mRNA processing factor 40 homolog A
  pre-mRNA processing factor 8
  retinoic acid induced 14
  Rho GTPase activating protein 11A
  Rhox homeobox family member 1
  ribonuclease P/MRP subunit p40
  ribosomal protein L13a
  ribosomal RNA processing 1
  ring finger protein 14
  RNA binding motif protein 25
  RNA binding motif protein 39
  RNA binding motif protein 5
  serine and arginine rich splicing factor 10
  serine and arginine rich splicing factor 11
  Sin3A associated protein 18
  SMU1 DNA replication regulator and spliceosomal factor
  splicing factor 3a subunit 1
  splicing factor 3b subunit 1
  splicing factor 3b subunit 3
  splicing factor 3b subunit 6
  ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
  syntrophin gamma 1
  TRIO and F-actin binding protein
  tRNA methyltransferase 11 homolog
  tubulin tyrosine ligase like 4
  ubiquilin 2
  ubiquitin specific peptidase 39
  uveal autoantigen with coiled-coil domains and ankyrin repeats
  WD repeat domain 18
  WD repeat domain 33
  zinc finger protein 483
  zinc finger protein 696
  zinc finger protein 777

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.