PRKRA, protein activator of interferon induced protein kinase EIF2AK2

PRKRA, protein activator of interferon induced protein kinase EIF2AK2

• This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

• Gene Synonyms (interferon-inducible double-stranded RNA-dependent protein kinase activator A, PKR-associated protein X, PKR-associating protein X, protein activator of the interferon-induced protein kinase, protein kinase, interferon-inducible double-stranded RNA-dependent activator, DYT16, HSD14, PACT, RAX,)
• NCBI Gene ID: 8575
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DJC7
  UNIPROT ID#>>O75569
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein activator of interferon induced protein kinase EIF2AK2 interacts with:

• argonaute RISC catalytic component 2
  beta-transducin repeat containing E3 ubiquitin protein ligase
  CCAAT enhancer binding protein zeta
  centrosomal protein 126
  chromosome 1 open reading frame 35
  coiled-coil domain containing 124
  COP9 signalosome subunit 6
  cullin associated and neddylation dissociated 1
  cyclic GMP-AMP synthase
  DExD/H-box helicase 58
  DExD-box helicase 50
  DGCR8 microprocessor complex subunit
  dicer 1, ribonuclease III
  EBNA1 binding protein 2
  EH domain containing 1
  Fas binding factor 1
  G3BP stress granule assembly factor 1
  GTP binding protein 4
  insulin like growth factor 2 mRNA binding protein 1
  integrin alpha FG-GAP repeat containing 1
  interferon induced with helicase C domain 1
  ligand of numb-protein X 1
  Ly1 antibody reactive
  MAGE family member B10
  mediator of DNA damage checkpoint 1
  mitogen-activated protein kinase kinase kinase 14
  NFKB repressing factor
  NHL repeat containing 2
  NOC3 like DNA replication regulator
  NOP16 nucleolar protein
  obscurin like cytoskeletal adaptor 1
  peptidylprolyl isomerase E
  pleckstrin homology domain containing A4
  protein activator of interferon induced protein kinase EIF2AK2
  protein inhibitor of activated STAT 2
  Rab9 effector protein with kelch motifs
  RALY RNA binding protein like
  RAS like family 10 member A
  ribosomal protein L36
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  RNA binding motif protein 34
  SET domain bifurcated histone lysine methyltransferase 1
  sirtuin 7
  sorting nexin 5
  spermatid perinuclear RNA binding protein
  SRSF protein kinase 3
  staufen double-stranded RNA binding protein 2
  synaptotagmin binding cytoplasmic RNA interacting protein
  TIR domain containing adaptor protein
  tripartite motif containing 28
  WD repeat domain 46
  WD repeat domain 5
  WW domain containing E3 ubiquitin protein ligase 2
  ZFP28 zinc finger protein
  zinc finger matrin-type 3
  zinc finger matrin-type 4
  zinc finger protein 346
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.