EMG1, EMG1 N1-specific pseudouridine methyltransferase

EMG1, EMG1 N1-specific pseudouridine methyltransferase

• This gene encodes an essential, conserved eukaryotic protein that methylates pseudouridine in 18S rRNA. The related protein in yeast is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

• Gene Synonyms (C2F, Grcc2f, NEP1, ribosomal RNA small subunit methyltransferase NEP1, 18S rRNA (pseudouridine(1248)-N1)-methyltransferase, 18S rRNA (pseudouridine-N1-)-methyltransferase NEP1, 18S rRNA Psi1248 methyltransferase, EMG1 nucleolar protein homolog, essential for mitotic growth 1, nucleolar essential protein 1, ribosome biogenesis protein NEP1,)
• NCBI Gene ID: 10436
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92979
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EMG1 N1-specific pseudouridine methyltransferase interacts with:

• autophagy related 16 like 1
  B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
  centrosomal protein 290
  decapping enzyme, scavenger
  EMG1 N1-specific pseudouridine methyltransferase
  eukaryotic translation initiation factor 3, subunit A
  exosome component 2
  exosome component 4
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  hyaluronan binding protein 4
  hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
  KH RNA binding domain containing, signal transduction associated 1
  microcephalin 1
  N-alpha-acetyltransferase 80, NatH catalytic subunit
  Nanog homeobox
  obscurin like cytoskeletal adaptor 1
  pre-mRNA processing factor 8
  ribosomal protein L35
  ribosome binding protein 1
  SERPINE1 mRNA binding protein 1
  solute carrier family 25 member 38
  transcription activation suppressor
  WD repeat domain 7
  zinc finger matrin-type 5
  zinc finger protein 768

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.