GGA3, golgi associated, gamma adaptin ear containing, ARF binding protein 3

GGA3, golgi associated, gamma adaptin ear containing, ARF binding protein 3

• This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]

• Gene Synonyms (ADP-ribosylation factor-binding protein GGA3, Golgi-localized, gamma ear-containing, ARF-binding protein 3,)
• NCBI Gene ID: 23163
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A8K6M0
  UNIPROT ID#>>B7Z456
  UNIPROT ID#>>Q9NZ52
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

golgi associated, gamma adaptin ear containing, ARF binding protein 3 interacts with:

• aftiphilin
  ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
  beta-secretase 1
  golgi associated, gamma adaptin ear containing, ARF binding protein 1
  golgi associated, gamma adaptin ear containing, ARF binding protein 3
  HAUS augmin like complex subunit 4
  itchy E3 ubiquitin protein ligase
  LDL receptor related protein 10
  phosphofurin acidic cluster sorting protein 1
  pleckstrin homology domain containing B2
  prolyl 4-hydroxylase subunit alpha 3
  ring finger protein 11
  ring finger protein 214
  stabilin 1
  TBC1 domain family member 3
  toll interacting protein
  trafficking protein particle complex 6A
  transmembrane protein 17
  uracil phosphoribosyltransferase homolog
  VPS11 core subunit of CORVET and HOPS complexes
  VPS18 core subunit of CORVET and HOPS complexes
  zinc finger protein 497

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.