GBP2, guanylate binding protein 2

GBP2, guanylate binding protein 2

• This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]

• Gene Synonyms (guanylate-binding protein 2, GTP-binding protein 2, guanine nucleotide-binding protein 2, guanylate binding protein 2, interferon-inducible, interferon-induced guanylate-binding protein 2,)
• NCBI Gene ID: 2634
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P32456
  UNIPROT ID#>>Q8TCE5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

guanylate binding protein 2 interacts with:

• BTB domain containing 2
  carnosine dipeptidase 2
  F-box protein 7
  FMR1 autosomal homolog 1
  galactosidase alpha
  glucosamine (N-acetyl)-6-sulfatase
  glutathione-disulfide reductase
  glycogen synthase kinase 3 beta
  guanylate binding protein 3
  guanylate binding protein 7
  heat shock protein 90 alpha family class A member 1
  heat shock protein 90 alpha family class B member 1
  heat shock protein family E (Hsp10) member 1
  hemoglobin subunit alpha 2
  kelch like family member 20
  LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
  membrane associated guanylate kinase, WW and PDZ domain containing 1
  mevalonate diphosphate decarboxylase
  mitogen-activated protein kinase 8 interacting protein 2
  N-acetylneuraminate synthase
  peptidase D
  platelet activating factor acetylhydrolase 1b catalytic subunit 3
  poly(rC) binding protein 3
  protein phosphatase 1 regulatory subunit 8
  ribosomal protein S6 kinase A1
  selenophosphate synthetase 1
  sequestosome 1
  serine/threonine kinase 3
  serpin family B member 9
  spermidine/spermine N1-acetyltransferase 1
  trafficking from ER to golgi regulator
  U2 small nuclear RNA auxiliary factor 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.