MAT2A, methionine adenosyltransferase 2A

MAT2A, methionine adenosyltransferase 2A

• The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]

• Gene Synonyms (MATA2, MATII, SAMS2, S-adenosylmethionine synthase isoform type-2, MAT 2, MAT-II, adoMet synthase 2, adoMet synthetase 2, methionine adenosyltransferase 2, methionine adenosyltransferase II, alpha, testicular tissue protein Li 121,)
• NCBI Gene ID: 4144
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A140VJP5
  UNIPROT ID#>>P31153
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

methionine adenosyltransferase 2A interacts with:

• AAR2 splicing factor
  actin, beta
  acyl-CoA synthetase short chain family member 2
  armadillo repeat containing 8
  autophagy related 16 like 1
  catenin beta like 1
  COP9 signalosome subunit 5
  cullin 3
  dynamin 1 like
  elongation factor Tu GTP binding domain containing 2
  ER membrane protein complex subunit 4
  exportin 1
  F-box protein 6
  golgi to ER traffic protein 4
  H3 clustered histone 6
  hepatocyte growth factor-regulated tyrosine kinase substrate
  inner membrane protein, mitochondrial
  integrator complex subunit 5
  MAGE family member F1
  methionine adenosyltransferase 2A
  methionine adenosyltransferase 2B
  methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
  methylphosphate capping enzyme
  minichromosome maintenance complex component 2
  MYC proto-oncogene, bHLH transcription factor
  neurotrophic receptor tyrosine kinase 1
  NMD3 ribosome export adaptor
  nuclear receptor subfamily 2 group C member 2
  parkin RBR E3 ubiquitin protein ligase
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  prohibitin
  protein regulator of cytokinesis 1
  RecQ like helicase 4
  ribosomal protein L35
  ribosomal protein S3
  ribosomal protein S3A
  septin 2
  SMAD specific E3 ubiquitin protein ligase 1
  snail family transcriptional repressor 1
  solute carrier family 33 member 1
  succinate dehydrogenase complex flavoprotein subunit A
  succinate dehydrogenase complex iron sulfur subunit B
  superoxide dismutase 1
  transmembrane protein 213
  tripartite motif containing 25
  tubulin alpha 1a
  tubulin beta class I
  ubiquitin conjugating enzyme E2 I
  ubiquitin conjugating enzyme E2 M
  UDP-glucose 6-dehydrogenase
  URI1 prefoldin like chaperone
  valosin containing protein lysine methyltransferase
  vir like m6A methyltransferase associated
  YY1 associated factor 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.