CRNKL1, crooked neck pre-mRNA splicing factor 1

CRNKL1, crooked neck pre-mRNA splicing factor 1

• The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013]

• Gene Synonyms (crooked neck-like protein 1, Crn, crooked neck-like 1, SYF3 pre-mRNA-splicing factor, crooked neck homolog, crooked neck pre-mRNA splicing factor-like 1, crooked neck-like 1, CLF, CRN, Clf1, HCRN, MSTP021, SYF3,)
• NCBI Gene ID: 51340
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q69YP1
  UNIPROT ID#>>Q9BZJ0
  UNIPROT ID#>>Q5JY65
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

crooked neck pre-mRNA splicing factor 1 interacts with:

• breast carcinoma amplified sequence 2
  cell division cycle 40
  cell division cycle 5-like (S. pombe)
  coiled-coil domain containing 12
  coiled-coil domain containing 12
  DnaJ heat shock protein family (Hsp40) member C17
  E2F associated phosphoprotein
  ISY1 splicing factor homolog
  ISY1 splicing factor homolog
  ISY1-RAB43 readthrough
  KIAA1143
  leucine zipper tumor suppressor 2
  mindbomb E3 ubiquitin protein ligase 1
  NKAP domain containing 1
  pleckstrin homology domain containing A4
  pre-mRNA processing factor 8
  PTEN induced kinase 1
  RALY RNA binding protein like
  sirtuin 7
  Smad nuclear interacting protein 1
  SNW domain containing 1
  U6 snRNA biogenesis phosphodiesterase 1
  WD repeat domain 83
  XPA binding protein 2
  YJU2 splicing factor homolog
  zinc finger CCCH-type containing 18

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.