RECQL, RecQ like helicase

RECQL, RecQ like helicase

• The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere maintenance, and is required for genotoxic stress resistance. Defects in this gene have been associated with several types of cancer. [provided by RefSeq, Jan 2017]

• Gene Synonyms (ATP-dependent DNA helicase Q1, DNA helicase, RecQ-like type 1, DNA-dependent ATPase Q1, RecQ helicase-like, RecQ protein-like (DNA helicase Q1-like), recQ protein-like 1, RECQL1, RecQ1,)
• NCBI Gene ID: 5965
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RAV2
  UNIPROT ID#>>P46063
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RecQ like helicase interacts with:

• BAF nuclear assembly factor 1
  elongation factor Tu GTP binding domain containing 2
  forkhead box I2
  golgi transport 1B
  H2B clustered histone 8
  H3 clustered histone 1
  integrin alpha FG-GAP repeat containing 1
  mab-21 like 2
  mediator complex subunit 20
  mediator of DNA damage checkpoint 1
  microtubule associated protein 7
  nuclear receptor subfamily 2 group C member 2
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  RecQ like helicase
  replication protein A1
  sirtuin 7
  small nuclear ribonucleoprotein U4/U6.U5 subunit 27
  staufen double-stranded RNA binding protein 1
  synaptotagmin binding cytoplasmic RNA interacting protein
  TEA domain transcription factor 2
  tripartite motif containing 28
  tumor protein p53 binding protein 1
  tumor protein, translationally-controlled 1
  ubiquitin C
  ubiquitin specific peptidase 47

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.