RFX3, regulatory factor X3

RFX3, regulatory factor X3

• This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]

• Gene Synonyms (transcription factor RFX3, DNA binding protein RFX3, regulatory factor X, 3 (influences HLA class II expression),)
• NCBI Gene ID: 5991
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P48380
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

regulatory factor X3 interacts with:

• acyl-CoA dehydrogenase family member 9
  cilia and flagella associated protein 20
  cyclin dependent kinase 20
  forkhead box J2
  immunoglobulin superfamily member 8
  metastasis associated 1 family member 2
  methyl-CpG binding domain protein 2
  MINDY lysine 48 deubiquitinase 3
  poly(A) binding protein cytoplasmic 5
  PTOV1 extended AT-hook containing adaptor protein
  regulatory factor X3
  regulatory factor X4
  regulatory factor X6
  RNA 2',3'-cyclic phosphate and 5'-OH ligase
  SEC63 homolog, protein translocation regulator
  SRY-box transcription factor 2
  TATA-box binding protein associated factor 6 like
  TBC1 domain family member 32
  thyroid hormone receptor interactor 6
  TNF receptor associated factor 2
  transmembrane p24 trafficking protein 4
  vacuolar protein sorting 45 homolog
  vir like m6A methyltransferase associated
  xylosyltransferase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.