RP2, RP2 activator of ARL3 GTPase

RP2, RP2 activator of ARL3 GTPase

• The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death [provided by RefSeq, Jul 2008]

• Gene Synonyms (protein XRP2, RP2, ARL3 GTPase activating protein, retinitis pigmentosa 2 (X-linked recessive), DELXp11.3, NM23-H10, NME10, TBCCD2, XRP2,)
• NCBI Gene ID: 6102
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A1B2JLU2
  UNIPROT ID#>>O75695
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RP2 activator of ARL3 GTPase interacts with:

• coiled-coil domain containing 8
  component of oligomeric golgi complex 7
  component of oligomeric golgi complex 8
  cytosolic thiouridylase subunit 1
  Dmx like 2
  Ecm29 proteasome adaptor and scaffold
  exportin 4
  exportin 7
  glomulin, FKBP associated protein
  importin 7
  integrator complex subunit 3
  kinetochore associated 1
  mitochondrial amidoxime reducing component 2
  non-SMC condensin I complex subunit H
  osteoclast stimulating factor 1
  PDS5 cohesin associated factor A
  peptidase M20 domain containing 2
  PRA1 domain family member 2
  protein only RNase P catalytic subunit
  signal transducer and activator of transcription 3
  solute carrier family 25 member 41
  solute carrier family 44 member 2
  symplekin
  TAR (HIV-1) RNA binding protein 1
  thioredoxin reductase 1
  thyroid hormone receptor interactor 12
  transcription factor CP2
  transducin beta like 3
  transportin 2
  transportin 3
  triokinase and FMN cyclase
  TSC complex subunit 2
  ubiquitin specific peptidase 24
  WD repeat domain 83
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.