CDC14A, cell division cycle 14A

CDC14A, cell division cycle 14A

• The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

• Gene Synonyms (dual specificity protein phosphatase CDC14A, CDC10 (cell division cycle 10, S. cerevisiae, homolog), CDC14 cell division cycle 14 homolog A, DFNB105, DFNB32, DFNB35, cdc14, hCDC14,)
• NCBI Gene ID: 8556
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DY86
  UNIPROT ID#>>Q9UNH5
  UNIPROT ID#>>Q59EF4
  UNIPROT ID#>>A0A0U1RQX7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cell division cycle 14A interacts with:

• 5'-3' exoribonuclease 1
  activating signal cointegrator 1 complex subunit 3
  apoptosis associated tyrosine kinase
  ATP binding cassette subfamily F member 2
  ATP synthase mitochondrial F1 complex assembly factor 2
  BMS1 ribosome biogenesis factor
  C2 domain containing 3 centriole elongation regulator
  centrobin, centriole duplication and spindle assembly protein
  centrosomal protein 131
  centrosomal protein 135
  centrosomal protein 162
  centrosomal protein 290
  centrosomal protein 350
  centrosome and spindle pole associated protein 1
  checkpoint kinase 2
  chromosome 14 open reading frame 119
  coiled-coil domain containing 61
  coiled-coil domain containing 77
  cullin 7
  cytoplasmic linker associated protein 1
  cytoskeleton associated protein 2
  cytoskeleton associated protein 5
  DEAD-box helicase 27
  DEAD-box helicase 54
  DIMT1 rRNA methyltransferase and ribosome maturation factor
  DNA polymerase delta interacting protein 3
  DNA topoisomerase III beta
  elongation factor like GTPase 1
  eukaryotic translation initiation factor 2 subunit beta
  eukaryotic translation initiation factor 2 subunit gamma B
  eukaryotic translation initiation factor 3 subunit A
  fizzy and cell division cycle 20 related 1
  insulin like growth factor 2 mRNA binding protein 2
  intraflagellar transport 172
  intraflagellar transport 57
  junctional cadherin 5 associated
  KIAA1328
  kinesin family member 20A
  KRI1 homolog
  lemur tyrosine kinase 2
  leucine rich pentatricopeptide repeat containing
  MAP7 domain containing 1
  microtubule associated protein RP/EB family member 2
  microtubule associated scaffold protein 1
  M-phase phosphoprotein 9
  MYC binding protein 2
  ninein
  peptidylprolyl isomerase like 4
  pleckstrin homology domain containing A7
  POC5 centriolar protein
  pre-mRNA processing factor 8
  protein phosphatase 6 regulatory subunit 1
  ribosomal RNA processing 1B
  RNA binding motif protein 26
  RNA binding motif protein 28
  serine and arginine repetitive matrix 1
  small nuclear ribonucleoprotein U5 subunit 200
  spindle and centriole associated protein 1
  splicing factor 3b subunit 2
  structural maintenance of chromosomes 4
  structural maintenance of chromosomes flexible hinge domain containing 1
  TBC1 domain family member 31
  tripartite motif containing 36
  tudor domain containing 3
  vir like m6A methyltransferase associated
  YTH domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.