TAX1BP1, Tax1 binding protein 1

TAX1BP1, Tax1 binding protein 1

• This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]

• Gene Synonyms (tax1-binding protein 1, TRAF6-binding protein, Tax1 (human T-cell leukemia virus type I) binding protein 1, CALCOCO3, T6BP, TXBP151,)
• NCBI Gene ID: 8887
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DSG5
  UNIPROT ID#>>Q86VP1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Tax1 binding protein 1 interacts with:

• 5-azacytidine induced 2
  argonaute RISC component 1
  calcium binding and coiled-coil domain 2
  centromere protein E
  chromobox 8
  chromosome 18 open reading frame 25
  component of oligomeric golgi complex 7
  COP1 E3 ubiquitin ligase
  CWF19 like cell cycle control factor 2
  CXXC finger protein 1
  cyclic GMP-AMP synthase
  cyclin Q
  DAZ associated protein 2
  destrin, actin depolymerizing factor
  DnaJ heat shock protein family (Hsp40) member C11
  elastin microfibril interfacer 1
  FAM161 centrosomal protein A
  family with sequence similarity 168 member A
  family with sequence similarity 189 member A2
  family with sequence similarity 90 member A1
  four and a half LIM domains 5
  GABA type A receptor associated protein like 1
  GABA type A receptor associated protein like 2
  GABA type A receptor-associated protein
  immunoglobulin like and fibronectin type III domain containing 1
  inhibitor of nuclear factor kappa B kinase subunit epsilon
  itchy E3 ubiquitin protein ligase
  KDEL endoplasmic reticulum protein retention receptor 1
  KN motif and ankyrin repeat domains 2
  L3MBTL histone methyl-lysine binding protein 2
  ligand of numb-protein X 1
  LIM domain only 3
  lipopolysaccharide induced TNF factor
  LRAT domain containing 2
  lysine acetyltransferase 5
  mediator complex subunit 4
  microtubule associated protein 1 light chain 3 beta
  microtubule associated protein 1 light chain 3 gamma
  mindbomb E3 ubiquitin protein ligase 1
  mitochondrial antiviral signaling protein
  mitochondrial ribosomal protein L11
  mitochondrial ribosomal protein L53
  nicotinamide riboside kinase 1
  N-terminal glutamine amidase 1
  optineurin
  pleckstrin homology domain containing B2
  pleckstrin homology domain containing N1
  progesterone immunomodulatory binding factor 1
  RAB guanine nucleotide exchange factor 1
  RAB18, member RAS oncogene family
  RAD18 E3 ubiquitin protein ligase
  RAD54 like 2
  RB1 inducible coiled-coil 1
  receptor accessory protein 4
  ring finger protein 11
  ring finger protein 115
  ring finger protein 126
  ring finger protein 26
  RNA polymerase I and III subunit C
  sodium channel modifier 1
  solute carrier family 22 member 23
  solute carrier family 5 member 12
  sprouty-related EVH1 domain containing 2
  StAR related lipid transfer domain containing 13
  TANK binding kinase 1
  Tax1 binding protein 1
  TBC1 domain family member 15
  TBC1 domain family member 17
  teashirt zinc finger homeobox 3
  TNF receptor associated factor 4
  TNFAIP3 interacting protein 1
  TNFAIP3 interacting protein 3
  trafficking protein particle complex 6A
  tripartite motif containing 14
  tripartite motif containing 45
  tRNA splicing endonuclease subunit 2
  TRPM8 channel associated factor 1
  ubiquitin associated and SH3 domain containing A
  ubiquitin specific peptidase 2
  upstream binding transcription factor like 1
  zinc finger protein 446

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.