AIP, aryl hydrocarbon receptor interacting protein

AIP, aryl hydrocarbon receptor interacting protein

• The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

• Gene Synonyms (AH receptor-interacting protein, Ah receptor activated 9, FK506-binding protein 37, FKBP prolyl isomerase 16, HBV X-associated protein 2, X-associated protein-2, aryl hydrocarbon receptor-associated protein 9, hepatitis B virus X-associated cellular protein 2, immunophilin homolog ARA9, ARA9, FKBP16, FKBP37, PITA1, SMTPHN, XAP-2, XAP2,)
• NCBI Gene ID: 9049
• Species: Homo sapiens (Human)
• UNIPROT ID#>>G9I2H4
  UNIPROT ID#>>O00170
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

aryl hydrocarbon receptor interacting protein interacts with:

• argonaute RISC component 1
  cell division cycle 37, HSP90 cochaperone
  coiled-coil domain containing 120
  C-type lectin domain containing 7A
  dual specificity phosphatase 16
  dynein axonemal assembly factor 2
  egl-9 family hypoxia inducible factor 3
  F-box protein 11
  G protein subunit alpha 13
  hypoxia inducible factor 1 subunit alpha inhibitor
  inorganic pyrophosphatase 2
  MKS transition zone complex subunit 1
  NAD synthetase 1
  nephrocystin 4
  neuraminidase 4
  NIMA related kinase 8
  PH domain and leucine rich repeat protein phosphatase 1
  pleckstrin homology domain containing A4
  PRAME family member 10
  PRAME family member 17
  prostaglandin E synthase 3
  protein phosphatase 6 regulatory subunit 2
  protein tyrosine phosphatase non-receptor type 18
  RecQ like helicase 4
  serine/threonine/tyrosine interacting like 1
  SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
  stress induced phosphoprotein 1
  TNNI3 interacting kinase
  translocase of outer mitochondrial membrane 20
  ubiquitin specific peptidase 19
  unc-51 like kinase 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.