ITGB5, integrin subunit beta 5

ITGB5, integrin subunit beta 5

• This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017]

• Gene Synonyms (integrin beta-5, testis secretory sperm-binding protein Li 217p,)
• NCBI Gene ID: 3693
• Species: Homo sapiens (Human)
• UNIPROT ID#>>D3DNA1
  UNIPROT ID#>>P18084
  UNIPROT ID#>>L7RT22
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

integrin subunit beta 5 interacts with:

• ADAM metallopeptidase domain 21
  ADAM metallopeptidase domain 33
  ADAM metallopeptidase domain 9
  amyloid beta precursor protein binding protein 2
  BCL2 like 13
  cullin 9
  cysteine rich tail 1
  cytochrome p450 oxidoreductase
  EGF containing fibulin extracellular matrix protein 2
  EGF like repeats and discoidin domains 3
  euchromatic histone lysine methyltransferase 2
  insulin like 5
  integrin subunit beta 3 binding protein
  integrin subunit beta 5
  kallikrein related peptidase 5
  keratin 31
  keratin 34
  keratin 40
  keratin associated protein 10-7
  keratin associated protein 10-8
  keratin associated protein 10-9
  keratin associated protein 1-1
  keratin associated protein 1-3
  keratin associated protein 3-2
  keratin associated protein 5-7
  latent transforming growth factor beta binding protein 1
  latent transforming growth factor beta binding protein 3
  leucine rich repeat containing 4
  MER proto-oncogene, tyrosine kinase
  metadherin
  microtubule associated scaffold protein 2
  milk fat globule EGF and factor V/VIII domain containing
  MYC proto-oncogene, bHLH transcription factor
  myosin X
  NBPF member 19
  notch 2 N-terminal like A
  NUMB endocytic adaptor protein
  p21 (RAC1) activated kinase 4
  palladin, cytoskeletal associated protein
  peroxisome proliferator activated receptor delta
  protein tyrosine kinase 2
  proteoglycan 3, pro eosinophil major basic protein 2
  proteolipid protein 1
  purinergic receptor P2Y2
  receptor for activated C kinase 1
  ring finger protein 4
  secreted phosphoprotein 1
  serine and arginine rich splicing factor 9
  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
  stabilin 2
  syntrophin alpha 1
  T cell immunoglobulin and mucin domain containing 4
  talin 1
  tensin 2
  vitronectin
  voltage dependent anion channel 3
  zinc finger and BTB domain containing 17
  zinc finger protein 655

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.