PSMD13, proteasome 26S subunit, non-ATPase 13

PSMD13, proteasome 26S subunit, non-ATPase 13

• The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

• Gene Synonyms (26S proteasome non-ATPase regulatory subunit 13, 26S proteasome regulatory subunit RPN9, 26S proteasome regulatory subunit S11, 26S proteasome regulatory subunit p40.5, 26S proteasome subunit p40.5, proteasome (prosome, macropain) 26S subunit, non-ATPase, 13, HSPC027, Rpn9, S11, p40.5,)
• NCBI Gene ID: 5719
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UNM6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

proteasome 26S subunit, non-ATPase 13 interacts with:

• adhesion regulating molecule 1
  anterior gradient 2, protein disulphide isomerase family member
  ATP binding cassette subfamily E member 1
  autophagy and beclin 1 regulator 1
  coiled-coil domain containing 74B
  coiled-coil domain containing 92
  crumbs cell polarity complex component 1
  dickkopf WNT signaling pathway inhibitor 1
  dual specificity phosphatase 15
  Ecm29 proteasome adaptor and scaffold
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  FKBP prolyl isomerase 8
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  heterogeneous nuclear ribonucleoprotein A0
  HEXIM P-TEFb complex subunit 1
  hypoxia inducible factor 1 subunit alpha inhibitor
  insulin induced gene 2
  inturned planar cell polarity protein
  kinase suppressor of ras 1
  La ribonucleoprotein 7, transcriptional regulator
  methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
  methylphosphate capping enzyme
  methyltransferase like 3
  pleckstrin homology domain containing A4
  potassium channel modulatory factor 1
  proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
  proteasome (prosome, macropain) subunit, beta type 5
  proteasome 20S subunit alpha 8
  proteasome 26S subunit, non-ATPase 13
  proteasome 26S subunit, non-ATPase 14
  proteasome 26S subunit, non-ATPase 6
  proteasome assembly chaperone 2
  protein tyrosine phosphatase non-receptor type 2
  protein tyrosine phosphatase non-receptor type 6
  protein tyrosine phosphatase receptor type M
  protein tyrosine phosphatase receptor type O
  protein tyrosine phosphatase receptor type U
  PTPRF interacting protein alpha 1
  RAD23 homolog A, nucleotide excision repair protein
  RAD23 homolog B, nucleotide excision repair protein
  RAN binding protein 9
  RB binding protein 4, chromatin remodeling factor
  RecQ like helicase 4
  retinoid isomerohydrolase RPE65
  ribosomal protein S21
  ribosomal protein S8
  ring finger protein 11
  SEM1 26S proteasome complex subunit
  SHANK associated RH domain interactor
  SNW domain containing 1
  solute carrier family 25 member 22
  SRSF protein kinase 2
  striatin 3
  striatin 4
  testis expressed 101
  thioredoxin like 1
  TNF receptor associated factor 6
  transforming growth factor beta receptor 2
  tumor protein p53 binding protein 1
  ubiquilin 2
  ubiquilin 4
  ubiquitin C
  ubiquitin conjugating enzyme E2 M
  ubiquitin C-terminal hydrolase L5
  ubiquitin like domain containing CTD phosphatase 1
  ubiquitin protein ligase E3 component n-recognin 4
  ubiquitin protein ligase E3A
  ubiquitin specific peptidase 14
  ubiquitin specific peptidase 15
  unc-45 myosin chaperone A
  vir like m6A methyltransferase associated
  von Hippel-Lindau tumor suppressor
  Yes1 associated transcriptional regulator
  zinc finger CCHC-type containing 8
  zinc finger FYVE-type containing 19
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.