TSSC4, tumor suppressing subtransferable candidate 4

TSSC4, tumor suppressing subtransferable candidate 4

• This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

• Gene Synonyms (protein TSSC4, tumor-suppressing STF cDNA 4 protein, tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein,)
• NCBI Gene ID: 10078
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y5U2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tumor suppressing subtransferable candidate 4 interacts with:

• AAR2 splicing factor
  arginine and serine rich coiled-coil 1
  atlastin GTPase 3
  autophagy related 16 like 1
  BCAS2 pre-mRNA processing factor
  CD2 cytoplasmic tail binding protein 2
  cell division cycle 40
  centrosomal protein 152
  centrosomal protein 76
  chromosome 1 open reading frame 112
  coiled-coil domain containing 12
  crooked neck pre-mRNA splicing factor 1
  CWC22 spliceosome associated protein homolog
  CWF19 like cell cycle control factor 1
  CWF19 like cell cycle control factor 2
  DEAH-box helicase 35
  E2F associated phosphoprotein
  ecdysoneless cell cycle regulator
  ecdysoneless cell cycle regulator
  egl-9 family hypoxia inducible factor 3
  G protein-coupled receptor 156
  GC-rich promoter binding protein 1 like 1
  germ cell-less 1, spermatogenesis associated
  G-patch domain containing 1
  ISY1 splicing factor homolog
  jun B proto-oncogene
  leucine zipper tumor suppressor 2
  neurochondrin
  PAX3 and PAX7 binding protein 1
  peptidylprolyl isomerase E
  pre-mRNA processing factor 19
  pre-mRNA processing factor 38A
  pre-mRNA processing factor 6
  pre-mRNA processing factor 8
  pre-mRNA processing factor 8
  protein phosphatase 4 regulatory subunit 2
  protein phosphatase 4 regulatory subunit 3A
  ring finger protein 31
  RNA binding motif protein 22
  RuvB like AAA ATPase 2
  RuvB-like protein 1
  SLU7 homolog, splicing factor
  small nuclear ribonucleoprotein U5 subunit 200
  SNW domain containing 1
  solute carrier family 7 member 6 opposite strand
  SYF2 pre-mRNA splicing factor
  TERF2 interacting protein
  TGF-beta activated kinase 1 (MAP3K7) binding protein 1
  thioredoxin like 4A
  tuftelin interacting protein 11
  tumor suppressing subtransferable candidate 4
  WASH complex subunit 1
  WD repeat domain 70
  WD repeat domain 83
  XPA binding protein 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.