POLD3, DNA polymerase delta 3, accessory subunit

POLD3, DNA polymerase delta 3, accessory subunit

• This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]

• Gene Synonyms (P66, P68, PPP1R128, DNA polymerase delta subunit 3, DNA polymerase delta subunit C, DNA polymerase delta subunit p66, DNA polymerase delta subunit p68, Pol delta C subunit (p66), polymerase (DNA) delta 3, accessory subunit, polymerase (DNA-directed), delta 3, accessory subunit, protein phosphatase 1, regulatory subunit 128,)
• NCBI Gene ID: 10714
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15054
  UNIPROT ID#>>A0A024R5M8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DNA polymerase delta 3, accessory subunit interacts with:

• cactin, spliceosome C complex subunit
  decapping mRNA 2
  DNA polymerase delta 3, accessory subunit
  DNA polymerase delta 4, accessory subunit
  Fas associated factor family member 2
  mediator complex subunit 10
  methyl-CpG binding domain protein 3 like 2
  pleckstrin homology domain containing A4
  proliferating cell nuclear antigen
  reticuloendotheliosis oncogene
  REV1 DNA directed polymerase
  sirtuin 6
  SprT-like N-terminal domain
  syntaxin binding protein 4
  tRNA splicing endonuclease subunit 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.