PWP1, PWP1 homolog, endonuclein

PWP1, PWP1 homolog, endonuclein

• The protein encoded by this gene contains several WD-40 repeats and is found mostly in the nucleus. The expression and localization of this protein are cell cycle dependent. Expression of this gene is upregulated in pancreatic adenocarcinoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

• Gene Synonyms (periodic tryptophan protein 1 homolog, endonuclein, keratinocyte protein IEF SSP 9502, nuclear phosphoprotein similar to S. cerevisiae PWP1, IEF-SSP-9502,)
• NCBI Gene ID: 11137
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DJV5
  UNIPROT ID#>>A0A024RBH5
  UNIPROT ID#>>Q13610
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PWP1 homolog, endonuclein interacts with:

• autophagy related 16 like 1
  bromodomain containing 7
  centrosomal protein 295
  cullin associated and neddylation dissociated 1
  cyclic GMP-AMP synthase
  DEAD-box helicase 24
  DET1 and DDB1 associated 1
  FtsJ RNA 2'-O-methyltransferase 3
  galectin 13
  GTP binding protein 4
  HMG-box transcription factor 1
  hyaluronan binding protein 4
  La ribonucleoprotein 7, transcriptional regulator
  lin-28 homolog A
  MDM2 binding protein
  obscurin like cytoskeletal adaptor 1
  pelota mRNA surveillance and ribosome rescue factor
  pescadillo ribosomal biogenesis factor 1
  proline rich 11
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  RNA binding motif protein 34
  SERPINE1 mRNA binding protein 1
  signal recognition particle 72
  sirtuin 7
  SMAD specific E3 ubiquitin protein ligase 1
  UTP20 small subunit processome component

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.