EYA2, EYA transcriptional coactivator and phosphatase 2

EYA2, EYA transcriptional coactivator and phosphatase 2

• This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may be post-translationally modified and may play a role in eye development. A similar protein in mice can act as a transcriptional activator. Alternative splicing results in multiple transcript variants, but the full-length natures of all of these variants have not yet been determined. [provided by RefSeq, Jul 2009]

• Gene Synonyms (EAB1, eyes absent homolog 2,)
• NCBI Gene ID: 2139
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O00167
  UNIPROT ID#>>E7ETN2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EYA transcriptional coactivator and phosphatase 2 interacts with:

• acyl-CoA dehydrogenase family member 9
  aldo-keto reductase family 7 member A2
  apoptosis associated tyrosine kinase
  argonaute RISC catalytic component 2
  AT-rich interaction domain 1A
  AT-rich interaction domain 1B
  BAG cochaperone 3
  BCL6 corepressor
  capicua transcriptional repressor
  cation channel sperm associated 1
  CCR4-NOT transcription complex subunit 1
  cell growth regulator with ring finger domain 1
  centrosomal protein 192
  centrosomal protein 85
  cingulin
  coiled-coil domain containing 18
  coiled-coil domain containing 28A
  coiled-coil domain containing 85C
  cyclin dependent kinase 18
  DDB1 and CUL4 associated factor 11
  deltex E3 ubiquitin ligase 2
  dermcidin
  DMRT like family B with proline rich C-terminal 1
  DnaJ heat shock protein family (Hsp40) member B12
  dual specificity phosphatase 21
  endosome associated trafficking regulator 1
  enkurin domain containing 1
  EYA transcriptional coactivator and phosphatase 2
  FAM3 metabolism regulating signaling molecule A
  family with sequence similarity 214 member B
  G protein subunit alpha i2
  G protein subunit alpha z
  G protein subunit beta 2
  galectin 4
  ganglioside induced differentiation associated protein 1
  GDP-mannose pyrophosphorylase A
  GDP-mannose pyrophosphorylase B
  glucose-6-phosphate isomerase
  glutaminyl-peptide cyclotransferase like
  glutathione peroxidase 8 (putative)
  Gse1 coiled-coil protein
  heat shock protein family D (Hsp60) member 1
  helicase with zinc finger
  hepatocyte growth factor-regulated tyrosine kinase substrate
  insulin degrading enzyme
  IQ motif and ubiquitin domain containing
  kinesin family member 14
  leucine zipper tumor suppressor 2
  lysine demethylase 6A
  lysine methyltransferase 2D
  matrix AAA peptidase interacting protein 1
  mediator complex subunit 25
  MIA SH3 domain ER export factor 3
  MMS19 homolog, cytosolic iron-sulfur assembly component
  NADH:ubiquinone oxidoreductase complex assembly factor 3
  NADH:ubiquinone oxidoreductase complex assembly factor 4
  NADH:ubiquinone oxidoreductase subunit A9
  natriuretic peptide C
  nibrin
  NME/NM23 nucleoside diphosphate kinase 1
  nuclear receptor corepressor 1
  nuclear receptor corepressor 2
  OXA1L mitochondrial inner membrane protein
  paired box 9
  peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  phosphatase and tensin homolog
  phosphatidylinositol glycan anchor biosynthesis class T
  phosphorylase kinase catalytic subunit gamma 2
  phosphorylase kinase regulatory subunit alpha 1
  phosphorylase kinase regulatory subunit alpha 2
  phosphorylase kinase regulatory subunit beta
  PNKD metallo-beta-lactamase domain containing
  pogo transposable element derived with ZNF domain
  POZ/BTB and AT hook containing zinc finger 1
  proline rich coiled-coil 2B
  prostaglandin E synthase 3
  proteasome activator subunit 3
  pumilio RNA binding family member 1
  receptor tyrosine kinase like orphan receptor 2
  regulatory factor X2
  ribonucleoprotein, PTB binding 1
  RNA binding motif protein 20
  RNA binding protein, mRNA processing factor
  SEC16 homolog A, endoplasmic reticulum export factor
  SIX homeobox 1
  SIX homeobox 2
  SIX homeobox 4
  small nuclear ribonucleoprotein polypeptide C
  solute carrier family 3 member 2
  sorting nexin 6
  SPG21 abhydrolase domain containing, maspardin
  sulfite oxidase
  synthesis of cytochrome C oxidase 1
  synthesis of cytochrome C oxidase 2
  tektin 4
  tektin 5
  testis specific serine kinase 3
  thioesterase superfamily member 6
  TLE family member 3, transcriptional corepressor
  TNF receptor associated factor 4
  trafficking from ER to golgi regulator
  trafficking protein particle complex 6A
  transcription factor AP-2 alpha
  transcriptional repressor GATA binding 1
  translocase of inner mitochondrial membrane 21
  transmembrane and coiled-coil domains 1
  transmembrane protein 9
  trinucleotide repeat containing adaptor 6A
  VAMP associated protein B and C
  VPS37C subunit of ESCRT-I
  zinc finger protein 609

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.