PITX1, paired like homeodomain 1

PITX1, paired like homeodomain 1

• This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. [provided by RefSeq, Jul 2008]

• Gene Synonyms (pituitary homeobox 1, hindlimb expressed homeobox protein backfoot, homeobox protein PITX1, paired-like homeodomain transcription factor 1, pituitary homeo box 1, pituitary otx-related factor, BFT, CCF, LBNBG, POTX, PTX1,)
• NCBI Gene ID: 5307
• Species: Homo sapiens (Human)
• UNIPROT ID#>>X5D9A5
  UNIPROT ID#>>P78337
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

paired like homeodomain 1 interacts with:

• abhydrolase domain containing 11
  A-kinase anchoring protein 8 like
  ALG13 UDP-N-acetylglucosaminyltransferase subunit
  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
  ankyrin repeat domain 10
  AT-rich interaction domain 5A
  BPI fold containing family A member 1
  chromosome 1 open reading frame 94
  chromosome 11 open reading frame 1
  chromosome 19 open reading frame 54
  chromosome 9 open reading frame 57
  cysteine rich tail 1
  DAZ interacting zinc finger protein 3
  dynactin subunit 3
  EGF containing fibulin extracellular matrix protein 2
  egl-9 family hypoxia inducible factor 3
  exportin 1
  family with sequence similarity 168 member A
  family with sequence similarity 168 member B
  H4 clustered histone 1
  hepatocyte growth factor-regulated tyrosine kinase substrate
  hydroxypyruvate isomerase (putative)
  IGF like family member 2
  importin 13
  kelch like family member 26
  keratin associated protein 13-1
  keratin associated protein 13-2
  keratin associated protein 19-5
  keratin associated protein 19-7
  keratin associated protein 26-1
  keratin associated protein 3-3
  keratin associated protein 6-1
  keratin associated protein 6-2
  keratin associated protein 6-3
  keratin associated protein 7-1
  keratin associated protein 8-1
  leucine zipper tumor suppressor 2
  MAGE family member D1
  methyltransferase like 27
  myosin heavy chain 7B
  myozenin 3
  NHL repeat containing 4
  nidogen 2
  phospholipase A2 group X
  phospholipid scramblase 1
  phospholipid scramblase 3
  pleckstrin homology domain containing A4
  pleckstrin homology domain containing B2
  POU class 1 homeobox 1
  proline rich 20A
  proline rich 20B
  proline rich 20C
  proline rich 20D
  proline rich 20E
  proteasome subunit beta 11
  protein phosphatase 1 catalytic subunit gamma
  protein tyrosine kinase 6
  RAS protein activator like 1
  regulatory factor X6
  Rhox homeobox family member 2
  ring finger protein 31
  RNA binding protein, mRNA processing factor
  saitohin
  salt inducible kinase 1B (putative)
  secretion regulating guanine nucleotide exchange factor
  solute carrier family 15 member 2
  sperm associated antigen 8
  SRY-box transcription factor 2
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  T-box transcription factor 19
  T-box transcription factor 22
  tektin 5
  TNF receptor associated factor 1
  trafficking protein particle complex 2
  transcription factor AP-2 delta
  TSC complex subunit 1
  tumor protein p53 binding protein 1
  tumor protein p63
  UFM1 specific peptidase 1 (inactive)
  UPF2 regulator of nonsense mediated mRNA decay
  vestigial like family member 3
  yippee like 3
  zinc finger and BTB domain containing 32
  zinc finger protein 34

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.