POU2F1, POU class 2 homeobox 1

POU2F1, POU class 2 homeobox 1

• The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010]

• Gene Synonyms (POU domain, class 2, transcription factor 1, NF-A1, OTF-1, Octamer-binding transcription factor-1, POU class 2 homeobox 1 isoform Oct-1R, oct-1, octamer-binding protein 1, octamer-binding transcription factor 1, OCT1, OTF1, oct-1B,)
• NCBI Gene ID: 5451
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R8Y2
  UNIPROT ID#>>P14859
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

POU class 2 homeobox 1 interacts with:

• actin related protein 2/3 complex subunit 3
  bromodomain containing 7
  diphosphoinositol pentakisphosphate kinase 2
  HNF1 homeobox A
  homeobox B13
  interferon regulatory factor 9
  MLLT10 histone lysine methyltransferase DOT1L cofactor
  nuclear receptor corepressor 2
  nuclear receptor subfamily 2 group F member 1
  pogo transposable element derived with ZNF domain
  POU class 2 homeobox 1
  POU class 6 homeobox 2
  pre B cell leukemia homeobox 1
  proline rich 20A
  proline rich 20B
  proline rich 20C
  proline rich 20D
  proline rich 20E
  protein kinase cAMP-activated catalytic subunit alpha
  protein kinase, DNA-activated, catalytic subunit
  RELA proto-oncogene, NF-kB subunit
  retinoic acid receptor alpha
  retinoid X receptor alpha
  signal transducer and activator of transcription 5A
  signal transducer and activator of transcription 5B
  Smad nuclear interacting protein 1
  small nuclear RNA activating complex polypeptide 4
  sorting nexin 24
  Sp1 transcription factor
  Sp4 transcription factor
  spectrin beta, non-erythrocytic 1
  SRY-box transcription factor 2
  storkhead box 1
  stress induced phosphoprotein 1
  TATA-box binding protein
  TEA domain transcription factor 2
  thioredoxin reductase 1
  thyroid hormone receptor alpha
  TLE family member 4, transcriptional corepressor
  tripartite motif containing 25
  tumor necrosis factor
  ubiquitin conjugating enzyme E2 I
  vir like m6A methyltransferase associated
  vitamin D receptor
  X-ray repair cross complementing 5
  zinc finger CCCH-type containing 10
  zinc finger MYM-type containing 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.