SRP68, signal recognition particle 68

SRP68, signal recognition particle 68

• This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, May 2012]

• Gene Synonyms (signal recognition particle subunit SRP68, signal recognition particle 68 kDa protein, signal recognition particle 68kD, signal recognition particle 68kDa,)
• NCBI Gene ID: 6730
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UHB9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

signal recognition particle 68 interacts with:

• ATPase family AAA domain containing 3B
  aurora kinase A interacting protein 1
  axonemal dynein light chain domain containing 1
  CCAAT enhancer binding protein zeta
  cullin 3
  cullin associated and neddylation dissociated 1
  cyclic GMP-AMP synthase
  DDB1 and CUL4 associated factor 15
  DEAD-box helicase 27
  DEAD-box helicase 31
  DISC1 scaffold protein
  EBNA1 binding protein 2
  elongation factor Tu GTP binding domain containing 2
  elongator acetyltransferase complex subunit 4
  exportin 1
  ezrin
  F-box protein 21
  fizzy and cell division cycle 20 related 1
  FtsJ RNA 2'-O-methyltransferase 3
  glucosylceramidase beta 2
  golgi brefeldin A resistant guanine nucleotide exchange factor 1
  GTP binding protein 4
  GTPase, IMAP family member 8
  HEXIM P-TEFb complex subunit 1
  kinesin family member 21A
  La ribonucleoprotein 7, transcriptional regulator
  limb development membrane protein 1 like
  lysine demethylase 3B
  mediator complex subunit 4
  methylphosphate capping enzyme
  methyltransferase like 18
  MYB binding protein 1a
  neuronal calcium sensor 1
  NOP56 ribonucleoprotein
  nuclear receptor subfamily 2 group C member 2
  nucleolar protein interacting with the FHA domain of MKI67
  pleckstrin homology domain containing A4
  PTEN induced kinase 1
  pumilio RNA binding family member 3
  RecQ like helicase 4
  ribosomal protein L26 like 1
  ring finger and CCCH-type domains 1
  ring finger protein 123
  ring finger protein 185
  RNA binding motif protein 28
  RNA binding motif protein 34
  signal recognition particle 72
  signal recognition particle 72
  sirtuin 7
  SNW domain containing 1
  splicing factor 3a subunit 3
  staphylococcal nuclease and tudor domain containing 1
  staufen double-stranded RNA binding protein 1
  testin LIM domain protein
  TNF receptor associated protein 1
  ubiquilin 2
  ubiquitin conjugating enzyme E2 N
  ubiquitin conjugating enzyme E2 S
  ubiquitin specific peptidase 7
  vir like m6A methyltransferase associated
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.